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Fibrinogens, Abnormal

"Fibrinogens, Abnormal" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

Fibrinogens which have a functional defect as the result of one or more amino acid substitutions in the amino acid sequence of normal fibrinogen. Abnormalities of the fibrinogen molecule may impair any of the major steps involved in the conversion of fibrinogen into stabilized fibrin, such as cleavage of the fibrinopeptides by thrombin, polymerization and cross-linking of fibrin. The resulting dysfibrinogenemias can be clinically silent or can be associated with bleeding, thrombosis or defective wound healing.


This graph shows the total number of publications written about "Fibrinogens, Abnormal" by people in Harvard Catalyst Profiles by year, and whether "Fibrinogens, Abnormal" was a major or minor topic of these publication.
Bar chart showing 8 publications over 6 distinct years, with a maximum of 2 publications in 2011 and 2012
To see the data from this visualization as text, click here.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.