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Farnesyl-Diphosphate Farnesyltransferase

"Farnesyl-Diphosphate Farnesyltransferase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

The first committed enzyme of the biosynthesis pathway that leads to the production of STEROLS. it catalyzes the synthesis of SQUALENE from farnesyl pyrophosphate via the intermediate PRESQUALENE PYROPHOSPHATE. This enzyme is also a critical branch point enzyme in the biosynthesis of ISOPRENOIDS that is thought to regulate the flux of isoprene intermediates through the sterol pathway.

This graph shows the total number of publications written about "Farnesyl-Diphosphate Farnesyltransferase" by people in Harvard Catalyst Profiles by year, and whether "Farnesyl-Diphosphate Farnesyltransferase" was a major or minor topic of these publication.
Bar chart showing 5 publications over 5 distinct years, with a maximum of 1 publications in 2002 and 2003 and 2004 and 2010 and 2019
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.