Factor V

"Factor V" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Heat- and storage-labile plasma glycoprotein which accelerates the conversion of prothrombin to thrombin in blood coagulation. Factor V accomplishes this by forming a complex with factor Xa, phospholipid, and calcium (prothrombinase complex). Deficiency of factor V leads to Owren's disease.

Descriptor ID

D005165

MeSH Number(s)

D12.776.124.125.300

D23.119.300

Concept/Terms

Factor V

Below are MeSH descriptors whose meaning is more general than "Factor V".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Blood Proteins [D12.776.124]
Blood Coagulation Factors [D12.776.124.125]
Factor V [D12.776.124.125.300]
Biological Factors [D23]
Blood Coagulation Factors [D23.119]
Factor V [D23.119.300]

Below are MeSH descriptors whose meaning is more specific than "Factor V".

Factor V
Factor Va

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Factor V" by people in Harvard Catalyst Profiles by year, and whether "Factor V" was a major or minor topic of these publication.

Bar chart showing 111 publications over 30 distinct years, with a maximum of 12 publications in 1997

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1993	0	1	1
1994	1	0	1
1995	3	1	4
1996	8	0	8
1997	11	1	12
1998	6	1	7
1999	6	2	8
2000	6	1	7
2001	2	1	3
2002	2	5	7
2003	3	4	7
2004	0	3	3
2005	2	0	2
2006	1	5	6
2007	3	1	4
2008	1	1	2
2009	1	2	3
2010	3	1	4
2011	2	3	5
2012	2	1	3
2013	1	0	1
2014	0	1	1
2015	0	2	2
2017	2	0	2
2018	1	0	1
2019	0	1	1
2020	3	0	3
2021	1	0	1
2022	0	1	1
2023	0	1	1

Below are the most recent publications written about "Factor V" by people in Profiles.

ADuLT: An efficient and robust time-to-event GWAS. Nat Commun. 2023 09 09; 14(1):5553.

View in: PubMed
ARF2-PIF5 interaction controls transcriptional reprogramming in the ABS3-mediated plant senescence pathway. EMBO J. 2022 10 04; 41(19):e110988.

View in: PubMed
Factor V mutation illuminates the dominant anticoagulant role and importance of an unidentified platelet modifier. J Thromb Haemost. 2021 05; 19(5):1168-1170.

View in: PubMed
Procoagulant activities of skeletal and cardiac muscle myosin depend on contaminating phospholipid. Blood. 2020 11 19; 136(21):2469-2472.

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Apixaban Does Not Interfere With Protein S or Activated Protein C Resistance (Factor V Leiden) Testing Using aPTT-Based Methods. Arch Pathol Lab Med. 2020 11 01; 144(11):1401-1407.

View in: PubMed
Marked factor V activity elevation in severe COVID-19 is associated with venous thromboembolism. Am J Hematol. 2020 12; 95(12):1522-1530.

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Association of Factor V Leiden With Subsequent Atherothrombotic Events: A GENIUS-CHD Study of Individual Participant Data. Circulation. 2020 08 11; 142(6):546-555.

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Comprehensive N- and O-glycosylation mapping of human coagulation factor V. J Thromb Haemost. 2020 08; 18(8):1884-1892.

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Acquired Factor V Deficiency Associated with CFPM Administration. Clin Lab. 2019 Oct 01; 65(10).

View in: PubMed
Recommendations for clinical laboratory testing of activated protein C resistance; communication from the SSC of the ISTH. J Thromb Haemost. 2019 09; 17(9):1555-1561.

View in: PubMed

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