Factor V

"Factor V" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Heat- and storage-labile plasma glycoprotein which accelerates the conversion of prothrombin to thrombin in blood coagulation. Factor V accomplishes this by forming a complex with factor Xa, phospholipid, and calcium (prothrombinase complex). Deficiency of factor V leads to Owren's disease.

Descriptor ID

D005165

MeSH Number(s)

D12.776.124.125.300

D23.119.300

Concept/Terms

Factor V

Below are MeSH descriptors whose meaning is more general than "Factor V".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Blood Proteins [D12.776.124]
Blood Coagulation Factors [D12.776.124.125]
Factor V [D12.776.124.125.300]
Biological Factors [D23]
Blood Coagulation Factors [D23.119]
Factor V [D23.119.300]

Below are MeSH descriptors whose meaning is more specific than "Factor V".

Factor V
Factor Va

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Factor V" by people in Harvard Catalyst Profiles by year, and whether "Factor V" was a major or minor topic of these publication.

Bar chart showing 128 publications over 29 distinct years, with a maximum of 11 publications in 1997

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1992	0	1	1
1993	0	1	1
1994	1	0	1
1995	3	1	4
1996	8	0	8
1997	10	1	11
1998	6	2	8
1999	6	2	8
2000	5	4	9
2001	2	1	3
2002	3	5	8
2003	3	5	8
2004	0	5	5
2005	3	1	4
2006	2	5	7
2007	3	1	4
2008	2	1	3
2009	2	2	4
2010	5	2	7
2011	2	3	5
2012	2	1	3
2013	2	0	2
2014	1	1	2
2015	1	2	3
2016	1	1	2
2017	1	0	1
2018	1	0	1
2019	1	2	3
2020	2	0	2

Below are the most recent publications written about "Factor V" by people in Profiles.

Maryamchik E, Van Cott EM. Apixaban Does Not Interfere With Protein S or Activated Protein C Resistance (Factor V Leiden) Testing Using aPTT-Based Methods. Arch Pathol Lab Med. 2020 11 01; 144(11):1401-1407.

View in: PubMed
Stefely JA, Christensen BB, Gogakos T, Cone Sullivan JK, Montgomery GG, Barranco JP, Van Cott EM. Marked factor V activity elevation in severe COVID-19 is associated with venous thromboembolism. Am J Hematol. 2020 12; 95(12):1522-1530.

View in: PubMed
Yamanishi M, Nishimi Y, Usui M, Miki K, Imashuku S. Acquired Factor V Deficiency Associated with CFPM Administration. Clin Lab. 2019 Oct 01; 65(10).

View in: PubMed
Moore GW, Van Cott EM, Cutler JA, Mitchell MJ, Adcock DM. Recommendations for clinical laboratory testing of activated protein C resistance; communication from the SSC of the ISTH. J Thromb Haemost. 2019 09; 17(9):1555-1561.

View in: PubMed
Klarin D, Lynch J, Aragam K, Chaffin M, Assimes TL, Huang J, Lee KM, Shao Q, Huffman JE, Natarajan P, Arya S, Small A, Sun YV, Vujkovic M, Freiberg MS, Wang L, Chen J, Saleheen D, Lee JS, Miller DR, Reaven P, Alba PR, Patterson OV, DuVall SL, Boden WE, Beckman JA, Gaziano JM, Concato J, Rader DJ, Cho K, Chang KM, Wilson PWF, O'Donnell CJ, Kathiresan S, Tsao PS, Damrauer SM. Genome-wide association study of peripheral artery disease in the Million Veteran Program. Nat Med. 2019 08; 25(8):1274-1279.

View in: PubMed
Alhazzani AA, Kumar A, Selim M. Association between Factor V Gene Polymorphism and Risk of Ischemic Stroke: An Updated Meta-Analysis. J Stroke Cerebrovasc Dis. 2018 May; 27(5):1252-1261.

View in: PubMed
Maryamchik E, Rosenbaum MW, Van Cott EM. Rivaroxaban Causes Missed Diagnosis of Protein S Deficiency but Not of Activated Protein C Resistance (Factor V Leiden). Arch Pathol Lab Med. 2018 Jan; 142(1):70-74.

View in: PubMed
Lang J, Vera D, Cheng Y, Tang H. Modeling Dengue Virus-Hepatic Cell Interactions Using Human Pluripotent Stem Cell-Derived Hepatocyte-like Cells. Stem Cell Reports. 2016 09 13; 7(3):341-354.

View in: PubMed
Smock KJ, Plumhoff EA, Meijer P, Hsu P, Zantek ND, Heikal NM, Van Cott EM. Protein S testing in patients with protein S deficiency, factor V Leiden, and rivaroxaban by North American Specialized Coagulation Laboratories. Thromb Haemost. 2016 07 04; 116(1):50-7.

View in: PubMed
Van Cott EM, Khor B, Zehnder JL. Factor V Leiden. Am J Hematol. 2016 Jan; 91(1):46-9.

View in: PubMed

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