Endothelium-Dependent Relaxing Factors

"Endothelium-Dependent Relaxing Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Paracrine substances produced by the VASCULAR ENDOTHELIUM with VASCULAR SMOOTH MUSCLE relaxation (VASODILATION) activities. Several factors have been identified, including NITRIC OXIDE and PROSTACYCLIN.

Descriptor ID

D045462

MeSH Number(s)

D27.505.954.411.918.500

Concept/Terms

Endothelium-Dependent Relaxing Factors

Neutrophil-Derived Relaxant Factor

Below are MeSH descriptors whose meaning is more general than "Endothelium-Dependent Relaxing Factors".

Chemicals and Drugs [D]
Chemical Actions and Uses [D27]
Pharmacologic Actions [D27.505]
Therapeutic Uses [D27.505.954]
Cardiovascular Agents [D27.505.954.411]
Vasodilator Agents [D27.505.954.411.918]
Endothelium-Dependent Relaxing Factors [D27.505.954.411.918.500]

Below are MeSH descriptors whose meaning is related to "Endothelium-Dependent Relaxing Factors".

Below are MeSH descriptors whose meaning is more specific than "Endothelium-Dependent Relaxing Factors".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Endothelium-Dependent Relaxing Factors" by people in Harvard Catalyst Profiles by year, and whether "Endothelium-Dependent Relaxing Factors" was a major or minor topic of these publication.

Below are the most recent publications written about "Endothelium-Dependent Relaxing Factors" by people in Profiles.

Protocol of a randomised controlled trial in cardiac surgical patients with endothelial dysfunction aimed to prevent postoperative acute kidney injury by administering nitric oxide gas. BMJ Open. 2019 07 04; 9(7):e026848.

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Recommendations for the Use of Inhaled Nitric Oxide Therapy in Premature Newborns with Severe Pulmonary Hypertension. J Pediatr. 2016 Mar; 170:312-4.

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Reactive oxygen species in endothelial function - from disease to adaptation - . Circ J. 2015; 79(6):1145-55.

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Our paper 20 years later: Inhaled nitric oxide for the acute respiratory distress syndrome--discovery, current understanding, and focussed targets of future applications. Intensive Care Med. 2014 Nov; 40(11):1649-58.

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Nitric oxide scavenging by red cell microparticles. Free Radic Biol Med. 2013 Dec; 65:1164-1173.

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The identification of nitric oxide as endothelium-derived relaxing factor. Circ Res. 2013 Jul 05; 113(2):100-3.

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Diabetes augments and inhaled nitric oxide prevents the adverse hemodynamic effects of transfusing syngeneic stored blood in mice. Transfusion. 2012 Jul; 52(7):1410-22.

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Hepatitis B virus X protein regulates hepatic glucose homeostasis via activation of inducible nitric oxide synthase. J Biol Chem. 2011 Aug 26; 286(34):29872-81.

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Nitric oxide for inhalation in the acute treatment of sickle cell pain crisis: a randomized controlled trial. JAMA. 2011 Mar 02; 305(9):893-902.

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Hypertension induced by vascular endothelial growth factor signaling pathway inhibition: mechanisms and potential use as a biomarker. Semin Nephrol. 2010 Nov; 30(6):591-601.

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