Endosomal Sorting Complexes Required for Transport
"Endosomal Sorting Complexes Required for Transport" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A set of protein subcomplexes involved in PROTEIN SORTING of UBIQUITINATED PROTEINS into intraluminal vesicles of MULTIVESICULAR BODIES and in membrane scission during formation of intraluminal vesicles, during the final step of CYTOKINESIS, and during the budding of enveloped viruses. The ESCRT machinery is comprised of the protein products of Class E vacuolar protein sorting genes.
MeSH Number(s)
D05.500.199
D12.776.543.990.493
Concept/Terms
Endosomal Sorting Complexes Required for Transport- Endosomal Sorting Complexes Required for Transport
- ESCRT Machinery
- Machinery, ESCRT
- ESCRT Complexes
- Complexes, ESCRT
- Endosomal Sorting Complex Required for Transport
- Endosomal Sorting Complex Required for Transport Machinery
Below are MeSH descriptors whose meaning is more general than "Endosomal Sorting Complexes Required for Transport".
Below are MeSH descriptors whose meaning is more specific than "Endosomal Sorting Complexes Required for Transport".
This graph shows the total number of publications written about "Endosomal Sorting Complexes Required for Transport" by people in Harvard Catalyst Profiles by year, and whether "Endosomal Sorting Complexes Required for Transport" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1997 | 0 | 2 | 2 |
| 1998 | 0 | 1 | 1 |
| 2000 | 0 | 4 | 4 |
| 2001 | 0 | 1 | 1 |
| 2003 | 0 | 2 | 2 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 5 | 5 |
| 2007 | 0 | 5 | 5 |
| 2008 | 0 | 4 | 4 |
| 2009 | 0 | 2 | 2 |
| 2010 | 2 | 2 | 4 |
| 2011 | 2 | 1 | 3 |
| 2012 | 4 | 2 | 6 |
| 2013 | 5 | 3 | 8 |
| 2014 | 3 | 2 | 5 |
| 2015 | 3 | 2 | 5 |
| 2016 | 5 | 0 | 5 |
| 2017 | 5 | 3 | 8 |
| 2018 | 5 | 4 | 9 |
| 2019 | 1 | 5 | 6 |
| 2020 | 4 | 1 | 5 |
| 2021 | 0 | 2 | 2 |
| 2022 | 1 | 2 | 3 |
Below are the most recent publications written about "Endosomal Sorting Complexes Required for Transport" by people in Profiles.
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TSG101 associates with PARP1 and is essential for PARylation and DNA damage-induced NF-?B activation. EMBO J. 2022 Nov 02; 41(21):e110372.
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CHMP2A regulates tumor sensitivity to natural killer cell-mediated cytotoxicity. Nat Commun. 2022 04 07; 13(1):1899.
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Tsg101/ESCRT-I recruitment regulated by the dual binding modes of K63-linked diubiquitin. Structure. 2022 02 03; 30(2):289-299.e6.
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A chemical genetics approach to examine the functions of AAA proteins. Nat Struct Mol Biol. 2021 04; 28(4):388-397.
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Direct binding of ESCRT protein Chm7 to phosphatidic acid-rich membranes at nuclear envelope herniations. J Cell Biol. 2021 03 01; 220(3).
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Membrane skeleton modulates erythroid proteome remodeling and organelle clearance. Blood. 2021 01 21; 137(3):398-409.
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Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q. Cell Rep. 2020 12 15; 33(11):108493.
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De Novo VPS4A Mutations Cause Multisystem Disease with Abnormal Neurodevelopment. Am J Hum Genet. 2020 12 03; 107(6):1129-1148.
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Factors promoting nuclear envelope assembly independent of the canonical ESCRT pathway. J Cell Biol. 2020 06 01; 219(6).
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PDCD6IP, encoding a regulator of the ESCRT complex, is mutated in microcephaly. Clin Genet. 2020 07; 98(1):80-85.