Encephalomyelitis, Autoimmune, Experimental
"Encephalomyelitis, Autoimmune, Experimental" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An experimental animal model for central nervous system demyelinating disease. Inoculation with a white matter emulsion combined with FREUND'S ADJUVANT, myelin basic protein, or purified central myelin triggers a T cell-mediated immune response directed towards central myelin. The pathologic features are similar to MULTIPLE SCLEROSIS, including perivascular and periventricular foci of inflammation and demyelination. Subpial demyelination underlying meningeal infiltrations also occurs, which is also a feature of ENCEPHALOMYELITIS, ACUTE DISSEMINATED. Passive immunization with T-cells from an afflicted animal to a normal animal also induces this condition. (From Immunol Res 1998;17(1-2):217-27; Raine CS, Textbook of Neuropathology, 2nd ed, p604-5)
MeSH Number(s)
C10.114.703.300
C10.228.140.695.562.250
C10.228.518.562.250
C10.314.350.250
C20.111.258.625.300
E05.598.500.500.500
Concept/Terms
Encephalomyelitis, Autoimmune, Experimental- Encephalomyelitis, Autoimmune, Experimental
- Allergic Encephalomyelitis, Experimental
- Encephalomyelitis, Experimental Allergic
- Experimental Allergic Encephalomyelitides
- Autoimmune Encephalomyelitis, Experimental
- Experimental Autoimmune Encephalomyelitis
- Encephalomyelitis, Allergic
- Encephalomyelitis, Experimental Autoimmune
- Experimental Allergic Encephalomyelitis
- Allergic Encephalomyelitis
- Autoimmune Experimental Encephalomyelitis
- Encephalomyelitis, Autoimmune Experimental
- Experimental Encephalomyelitis, Autoimmune
Below are MeSH descriptors whose meaning is more general than "Encephalomyelitis, Autoimmune, Experimental".
- Diseases [C]
- Nervous System Diseases [C10]
- Autoimmune Diseases of the Nervous System [C10.114]
- Nervous System Autoimmune Disease, Experimental [C10.114.703]
- Encephalomyelitis, Autoimmune, Experimental [C10.114.703.300]
- Central Nervous System Diseases [C10.228]
- Brain Diseases [C10.228.140]
- Leukoencephalopathies [C10.228.140.695]
- Demyelinating Autoimmune Diseases, CNS [C10.228.140.695.562]
- Encephalomyelitis, Autoimmune, Experimental [C10.228.140.695.562.250]
- Leukoencephalopathies [C10.228.518]
- Demyelinating Autoimmune Diseases, CNS [C10.228.518.562]
- Encephalomyelitis, Autoimmune, Experimental [C10.228.518.562.250]
- Demyelinating Diseases [C10.314]
- Demyelinating Autoimmune Diseases, CNS [C10.314.350]
- Encephalomyelitis, Autoimmune, Experimental [C10.314.350.250]
- Immune System Diseases [C20]
- Autoimmune Diseases [C20.111]
- Autoimmune Diseases of the Nervous System [C20.111.258]
- Nervous System Autoimmune Disease, Experimental [C20.111.258.625]
- Encephalomyelitis, Autoimmune, Experimental [C20.111.258.625.300]
- Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
- Investigative Techniques [E05]
- Models, Animal [E05.598]
- Disease Models, Animal [E05.598.500]
- Nervous System Autoimmune Disease, Experimental [E05.598.500.500]
- Encephalomyelitis, Autoimmune, Experimental [E05.598.500.500.500]
Below are MeSH descriptors whose meaning is more specific than "Encephalomyelitis, Autoimmune, Experimental".
This graph shows the total number of publications written about "Encephalomyelitis, Autoimmune, Experimental" by people in Harvard Catalyst Profiles by year, and whether "Encephalomyelitis, Autoimmune, Experimental" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 6 | 1 | 7 |
| 1994 | 8 | 1 | 9 |
| 1995 | 5 | 4 | 9 |
| 1996 | 11 | 2 | 13 |
| 1997 | 5 | 1 | 6 |
| 1998 | 10 | 1 | 11 |
| 1999 | 9 | 3 | 12 |
| 2000 | 8 | 4 | 12 |
| 2001 | 13 | 5 | 18 |
| 2002 | 4 | 5 | 9 |
| 2003 | 11 | 5 | 16 |
| 2004 | 11 | 7 | 18 |
| 2005 | 9 | 2 | 11 |
| 2006 | 8 | 2 | 10 |
| 2007 | 14 | 5 | 19 |
| 2008 | 13 | 7 | 20 |
| 2009 | 13 | 2 | 15 |
| 2010 | 13 | 5 | 18 |
| 2011 | 11 | 8 | 19 |
| 2012 | 13 | 1 | 14 |
| 2013 | 11 | 9 | 20 |
| 2014 | 12 | 9 | 21 |
| 2015 | 18 | 7 | 25 |
| 2016 | 15 | 9 | 24 |
| 2017 | 8 | 4 | 12 |
| 2018 | 12 | 3 | 15 |
| 2019 | 19 | 3 | 22 |
| 2020 | 7 | 5 | 12 |
| 2021 | 13 | 6 | 19 |
| 2022 | 10 | 0 | 10 |
Below are the most recent publications written about "Encephalomyelitis, Autoimmune, Experimental" by people in Profiles.
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Mining the microbiota to identify gut commensals modulating neuroinflammation in a mouse model of multiple sclerosis. Microbiome. 2022 10 17; 10(1):174.
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Metabolic regulation and function of T helper cells in neuroinflammation. Semin Immunopathol. 2022 09; 44(5):581-598.
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Anti-Caspr-conjugated gold nanoparticles emergence as a novel approach in the treatment of EAE animal model. Metab Brain Dis. 2022 10; 37(7):2603-2613.
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microRNA-92a promotes CNS autoimmunity by modulating the regulatory and inflammatory T cell balance. J Clin Invest. 2022 05 16; 132(10).
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The C-type lectin receptor Clec1A plays an important role in the development of experimental autoimmune encephalomyelitis by enhancing antigen presenting ability of dendritic cells and inducing inflammatory cytokine IL-17. Exp Anim. 2022 Aug 05; 71(3):288-304.
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Fibrin-targeting molecular MRI in inflammatory CNS disorders. Eur J Nucl Med Mol Imaging. 2022 09; 49(11):3692-3704.
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Oral tolerance: an updated review. Immunol Lett. 2022 05; 245:29-37.
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Tim-3 adapter protein Bat3 acts as an endogenous regulator of tolerogenic dendritic cell function. Sci Immunol. 2022 03 11; 7(69):eabm0631.
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Hemostasis Components as Therapeutic Targets in Autoimmune Demyelination. Clin Pharmacol Ther. 2022 04; 111(4):807-816.
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Treatment of Experimental Autoimmune Encephalomyelitis with an Inhibitor of Phosphodiesterase-8 (PDE8). Cells. 2022 02 14; 11(4).