Encephalomyelitis, Autoimmune, Experimental
"Encephalomyelitis, Autoimmune, Experimental" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An experimental animal model for central nervous system demyelinating disease. Inoculation with a white matter emulsion combined with FREUND'S ADJUVANT, myelin basic protein, or purified central myelin triggers a T cell-mediated immune response directed towards central myelin. The pathologic features are similar to MULTIPLE SCLEROSIS, including perivascular and periventricular foci of inflammation and demyelination. Subpial demyelination underlying meningeal infiltrations also occurs, which is also a feature of ENCEPHALOMYELITIS, ACUTE DISSEMINATED. Passive immunization with T-cells from an afflicted animal to a normal animal also induces this condition. (From Immunol Res 1998;17(1-2):217-27; Raine CS, Textbook of Neuropathology, 2nd ed, p604-5)
MeSH Number(s)
C10.114.703.300
C10.228.140.695.562.250
C10.228.518.562.250
C10.314.350.250
C20.111.258.625.300
E05.598.500.500.500
Concept/Terms
Encephalomyelitis, Autoimmune, Experimental- Encephalomyelitis, Autoimmune, Experimental
- Allergic Encephalomyelitis, Experimental
- Encephalomyelitis, Experimental Allergic
- Experimental Allergic Encephalomyelitides
- Autoimmune Encephalomyelitis, Experimental
- Experimental Autoimmune Encephalomyelitis
- Encephalomyelitis, Allergic
- Encephalomyelitis, Experimental Autoimmune
- Experimental Allergic Encephalomyelitis
- Allergic Encephalomyelitis
- Autoimmune Experimental Encephalomyelitis
- Encephalomyelitis, Autoimmune Experimental
- Experimental Encephalomyelitis, Autoimmune
Below are MeSH descriptors whose meaning is more general than "Encephalomyelitis, Autoimmune, Experimental".
- Diseases [C]
- Nervous System Diseases [C10]
- Autoimmune Diseases of the Nervous System [C10.114]
- Nervous System Autoimmune Disease, Experimental [C10.114.703]
- Encephalomyelitis, Autoimmune, Experimental [C10.114.703.300]
- Central Nervous System Diseases [C10.228]
- Brain Diseases [C10.228.140]
- Leukoencephalopathies [C10.228.140.695]
- Demyelinating Autoimmune Diseases, CNS [C10.228.140.695.562]
- Encephalomyelitis, Autoimmune, Experimental [C10.228.140.695.562.250]
- Leukoencephalopathies [C10.228.518]
- Demyelinating Autoimmune Diseases, CNS [C10.228.518.562]
- Encephalomyelitis, Autoimmune, Experimental [C10.228.518.562.250]
- Demyelinating Diseases [C10.314]
- Demyelinating Autoimmune Diseases, CNS [C10.314.350]
- Encephalomyelitis, Autoimmune, Experimental [C10.314.350.250]
- Immune System Diseases [C20]
- Autoimmune Diseases [C20.111]
- Autoimmune Diseases of the Nervous System [C20.111.258]
- Nervous System Autoimmune Disease, Experimental [C20.111.258.625]
- Encephalomyelitis, Autoimmune, Experimental [C20.111.258.625.300]
- Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
- Investigative Techniques [E05]
- Models, Animal [E05.598]
- Disease Models, Animal [E05.598.500]
- Nervous System Autoimmune Disease, Experimental [E05.598.500.500]
- Encephalomyelitis, Autoimmune, Experimental [E05.598.500.500.500]
Below are MeSH descriptors whose meaning is more specific than "Encephalomyelitis, Autoimmune, Experimental".
This graph shows the total number of publications written about "Encephalomyelitis, Autoimmune, Experimental" by people in Harvard Catalyst Profiles by year, and whether "Encephalomyelitis, Autoimmune, Experimental" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 5 | 1 | 6 |
| 1992 | 7 | 1 | 8 |
| 1993 | 6 | 1 | 7 |
| 1994 | 8 | 1 | 9 |
| 1995 | 5 | 4 | 9 |
| 1996 | 11 | 2 | 13 |
| 1997 | 5 | 1 | 6 |
| 1998 | 10 | 1 | 11 |
| 1999 | 9 | 3 | 12 |
| 2000 | 8 | 4 | 12 |
| 2001 | 11 | 4 | 15 |
| 2002 | 4 | 5 | 9 |
| 2003 | 11 | 5 | 16 |
| 2004 | 12 | 7 | 19 |
| 2005 | 9 | 2 | 11 |
| 2006 | 8 | 2 | 10 |
| 2007 | 15 | 5 | 20 |
| 2008 | 14 | 6 | 20 |
| 2009 | 14 | 3 | 17 |
| 2010 | 12 | 5 | 17 |
| 2011 | 11 | 8 | 19 |
| 2012 | 12 | 4 | 16 |
| 2013 | 8 | 9 | 17 |
| 2014 | 13 | 8 | 21 |
| 2015 | 19 | 7 | 26 |
| 2016 | 14 | 8 | 22 |
| 2017 | 8 | 5 | 13 |
| 2018 | 14 | 4 | 18 |
| 2019 | 17 | 4 | 21 |
| 2020 | 4 | 2 | 6 |
Below are the most recent publications written about "Encephalomyelitis, Autoimmune, Experimental" by people in Profiles.
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Tolerogenic nanoparticles suppress central nervous system inflammation. Proc Natl Acad Sci U S A. 2020 12 15; 117(50):32017-32028.
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Activin-A limits Th17 pathogenicity and autoimmune neuroinflammation via CD39 and CD73 ectonucleotidases and Hif1-a-dependent pathways. Proc Natl Acad Sci U S A. 2020 06 02; 117(22):12269-12280.
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TAGAP instructs Th17 differentiation by bridging Dectin activation to EPHB2 signaling in innate antifungal response. Nat Commun. 2020 04 20; 11(1):1913.
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Insulin-Like Growth Factors Are Key Regulators of T Helper 17 Regulatory T Cell Balance in Autoimmunity. Immunity. 2020 04 14; 52(4):650-667.e10.
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MAFG-driven astrocytes promote CNS inflammation. Nature. 2020 02; 578(7796):593-599.
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Endogenous T Cell Receptor Rearrangement Represses Aggressive Central Nervous System Autoimmunity in a TcR-Transgenic Model on the Non-Obese Diabetic Background. Front Immunol. 2019; 10:3115.
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Role of SOCS2 in the Regulation of Immune Response and Development of the Experimental Autoimmune Encephalomyelitis. Mediators Inflamm. 2019; 2019:1872593.
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Metabolic Control of Astrocyte Pathogenic Activity via cPLA2-MAVS. Cell. 2019 12 12; 179(7):1483-1498.e22.
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Oral Administration of miR-30d from Feces of MS Patients Suppresses MS-like Symptoms in Mice by Expanding Akkermansia muciniphila. Cell Host Microbe. 2019 12 11; 26(6):779-794.e8.
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?d T Cell-Secreted XCL1 Mediates Anti-CD3-Induced Oral Tolerance. J Immunol. 2019 11 15; 203(10):2621-2629.