E2F1 Transcription Factor

"E2F1 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

An E2F transcription factor that interacts directly with RETINOBLASTOMA PROTEIN and CYCLIN A and activates GENETIC TRANSCRIPTION required for CELL CYCLE entry and DNA synthesis. E2F1 is involved in DNA REPAIR and APOPTOSIS.

Descriptor ID

D050687

MeSH Number(s)

D12.644.360.024.328.049

D12.776.157.057.158.049

D12.776.476.024.414.049

D12.776.660.769.049

D12.776.930.311.500

Concept/Terms

E2F1 Transcription Factor

Below are MeSH descriptors whose meaning is more general than "E2F1 Transcription Factor".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intracellular Signaling Peptides and Proteins [D12.644.360]
Adaptor Proteins, Signal Transducing [D12.644.360.024]
Retinoblastoma Binding Proteins [D12.644.360.024.328]
E2F1 Transcription Factor [D12.644.360.024.328.049]
Proteins [D12.776]
Carrier Proteins [D12.776.157]
Adaptor Proteins, Signal Transducing [D12.776.157.057]
Retinoblastoma Binding Proteins [D12.776.157.057.158]
E2F1 Transcription Factor [D12.776.157.057.158.049]
Intracellular Signaling Peptides and Proteins [D12.776.476]
Adaptor Proteins, Signal Transducing [D12.776.476.024]
Retinoblastoma Binding Proteins [D12.776.476.024.414]
E2F1 Transcription Factor [D12.776.476.024.414.049]
Nuclear Proteins [D12.776.660]
Retinoblastoma Binding Proteins [D12.776.660.769]
E2F1 Transcription Factor [D12.776.660.769.049]
Transcription Factors [D12.776.930]
E2F Transcription Factors [D12.776.930.311]
E2F1 Transcription Factor [D12.776.930.311.500]

Below are MeSH descriptors whose meaning is related to "E2F1 Transcription Factor".

Below are MeSH descriptors whose meaning is more specific than "E2F1 Transcription Factor".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "E2F1 Transcription Factor" by people in Harvard Catalyst Profiles by year, and whether "E2F1 Transcription Factor" was a major or minor topic of these publication.

Bar chart showing 125 publications over 28 distinct years, with a maximum of 10 publications in 2000

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1993	0	7	7
1994	0	7	7
1995	0	9	9
1996	0	8	8
1997	0	3	3
1998	0	2	2
1999	0	3	3
2000	0	10	10
2001	0	9	9
2002	0	6	6
2003	0	6	6
2004	0	2	2
2006	4	2	6
2008	3	2	5
2009	2	0	2
2010	1	1	2
2011	1	0	1
2012	3	1	4
2013	0	3	3
2014	2	3	5
2015	3	2	5
2016	1	2	3
2017	1	2	3
2018	0	3	3
2019	1	2	3
2020	0	2	2
2021	1	0	1
2022	2	3	5

Below are the most recent publications written about "E2F1 Transcription Factor" by people in Profiles.

Metformin alleviates bone loss in ovariectomized mice through inhibition of autophagy of osteoclast precursors mediated by E2F1. Cell Commun Signal. 2022 10 25; 20(1):165.

View in: PubMed
E2F1 transcription factor mediates a link between fat and islets to promote ß cell proliferation in response to acute insulin resistance. Cell Rep. 2022 10 04; 41(1):111436.

View in: PubMed
Chromatin-bound RB targets promoters, enhancers, and CTCF-bound loci and is redistributed by cell-cycle progression. Mol Cell. 2022 09 15; 82(18):3333-3349.e9.

View in: PubMed
The Yun/Prohibitin complex regulates adult Drosophila intestinal stem cell proliferation through the transcription factor E2F1. Proc Natl Acad Sci U S A. 2022 02 08; 119(6).

View in: PubMed
E2F and STAT3 provide transcriptional synergy for histone variant H2AZ activation to sustain glioblastoma chromatin accessibility and tumorigenicity. Cell Death Differ. 2022 07; 29(7):1379-1394.

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BET Bromodomain Inhibition Blocks an AR-Repressed, E2F1-Activated Treatment-Emergent Neuroendocrine Prostate Cancer Lineage Plasticity Program. Clin Cancer Res. 2021 09 01; 27(17):4923-4936.

View in: PubMed
Macrophage secretion of miR-106b-5p causes renin-dependent hypertension. Nat Commun. 2020 09 23; 11(1):4798.

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The oncofetal RNA-binding protein IGF2BP1 is a druggable, post-transcriptional super-enhancer of E2F-driven gene expression in cancer. Nucleic Acids Res. 2020 09 04; 48(15):8576-8590.

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ZBTB7A Mediates the Transcriptional Repression Activity of the Androgen Receptor in Prostate Cancer. Cancer Res. 2019 10 15; 79(20):5260-5271.

View in: PubMed
PARP Inhibition Suppresses GR-MYCN-CDK5-RB1-E2F1 Signaling and Neuroendocrine Differentiation in Castration-Resistant Prostate Cancer. Clin Cancer Res. 2019 11 15; 25(22):6839-6851.

View in: PubMed

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