Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Dystrophin

"Dystrophin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

A muscle protein localized in surface membranes which is the product of the Duchenne/Becker muscular dystrophy gene. Individuals with Duchenne muscular dystrophy usually lack dystrophin completely while those with Becker muscular dystrophy have dystrophin of an altered size. It shares features with other cytoskeletal proteins such as SPECTRIN and alpha-actinin but the precise function of dystrophin is not clear. One possible role might be to preserve the integrity and alignment of the plasma membrane to the myofibrils during muscle contraction and relaxation. MW 400 kDa.


This graph shows the total number of publications written about "Dystrophin" by people in Harvard Catalyst Profiles by year, and whether "Dystrophin" was a major or minor topic of these publication.
Bar chart showing 196 publications over 30 distinct years, with a maximum of 18 publications in 1989
To see the data from this visualization as text, click here.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.