"Dysgerminoma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A malignant ovarian neoplasm, thought to be derived from primordial germ cells of the sexually undifferentiated embryonic gonad. It is the counterpart of the classical seminoma of the testis, to which it is both grossly and histologically identical. Dysgerminomas comprise 16% of all germ cell tumors but are rare before the age of 10, although nearly 50% occur before the age of 20. They are generally considered of low-grade malignancy but may spread if the tumor extends through its capsule and involves lymph nodes or blood vessels. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1646)
Concept/Terms
Dysgerminoma- Dysgerminoma
- Dysgerminomas
- Disgerminoma
- Disgerminomas
Below are MeSH descriptors whose meaning is more general than "Dysgerminoma".
Below are MeSH descriptors whose meaning is more specific than "Dysgerminoma".
This graph shows the total number of publications written about "Dysgerminoma" by people in Harvard Catalyst Profiles by year, and whether "Dysgerminoma" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 2 | 0 | 2 |
| 1999 | 1 | 0 | 1 |
| 2004 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2018 | 1 | 1 | 2 |
| 2021 | 1 | 1 | 2 |
Below are the most recent publications written about "Dysgerminoma" by people in Profiles.
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Dysgerminoma of the Ovary: An Analysis of 140 Cases Emphasizing Unusual Microscopic Findings and Resultant Diagnostic Problems. Am J Surg Pathol. 2021 08 01; 45(8):1009-1027.
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Malignant Mixed Germ Cell Tumors of the Ovary: An Analysis of 100 Cases Emphasizing the Frequency and Interrelationships of Their Tumor Types. Am J Surg Pathol. 2021 06 01; 45(6):727-741.
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Differences in DNA methylation profiles by histologic subtype of paediatric germ cell tumours: a report from the Children's Oncology Group. Br J Cancer. 2018 10; 119(7):864-872.
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Is carboplatin-based chemotherapy as effective as cisplatin-based chemotherapy in the treatment of advanced-stage dysgerminoma in children, adolescents and young adults? Gynecol Oncol. 2018 08; 150(2):253-260.
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Conundrums in the management of malignant ovarian germ cell tumors: Toward lessening acute morbidity and late effects of treatment. Gynecol Oncol. 2016 Nov; 143(2):428-432.
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The microenvironment of germ cell tumors harbors a prominent antigen-driven humoral response. J Immunol. 2009 Mar 01; 182(5):3310-7.
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The role of leptin, soluble leptin receptor, resistin, and insulin secretory dynamics in the pathogenesis of hypothalamic obesity in children. Eur J Pediatr. 2009 Sep; 168(9):1043-8.
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Increased expression of 25-hydroxyvitamin D-1alpha-hydroxylase in dysgerminomas: a novel form of humoral hypercalcemia of malignancy. Am J Pathol. 2004 Sep; 165(3):807-13.
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KIT mutations are common in testicular seminomas. Am J Pathol. 2004 Jan; 164(1):305-13.
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Age at immigration and duration of stay in relation to risk for testicular cancer among Finnish immigrants in Sweden. J Natl Cancer Inst. 2003 Aug 20; 95(16):1238-40.