Harvard Catalyst Profiles

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Drug Tolerance

"Drug Tolerance" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

Progressive diminution of the susceptibility of a human or animal to the effects of a drug, resulting from its continued administration. It should be differentiated from DRUG RESISTANCE wherein an organism, disease, or tissue fails to respond to the intended effectiveness of a chemical or drug. It should also be differentiated from MAXIMUM TOLERATED DOSE and NO-OBSERVED-ADVERSE-EFFECT LEVEL.


This graph shows the total number of publications written about "Drug Tolerance" by people in Harvard Catalyst Profiles by year, and whether "Drug Tolerance" was a major or minor topic of these publication.
Bar chart showing 253 publications over 31 distinct years, with a maximum of 17 publications in 2002
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.