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Disintegrins

"Disintegrins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

A family of polypeptides purified from snake venoms, which contain the arginine-glycine-aspartic acid (RGD) sequence. The RGD tripeptide binds to integrin receptors and thus competitively inhibits normal integrin-ligand interactions. Disintegrins thus block adhesive functions and act as platelet aggregation inhibitors.


This graph shows the total number of publications written about "Disintegrins" by people in Harvard Catalyst Profiles by year, and whether "Disintegrins" was a major or minor topic of these publication.
Bar chart showing 17 publications over 14 distinct years, with a maximum of 2 publications in 2004 and 2019 and 2022
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.