Harvard Catalyst Profiles

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Dextromethorphan

"Dextromethorphan" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

Methyl analog of DEXTRORPHAN that shows high affinity binding to several regions of the brain, including the medullary cough center. This compound is an NMDA receptor antagonist (RECEPTORS, N-METHYL-D-ASPARTATE) and acts as a non-competitive channel blocker. It is one of the widely used ANTITUSSIVES, and is also used to study the involvement of glutamate receptors in neurotoxicity.


This graph shows the total number of publications written about "Dextromethorphan" by people in Harvard Catalyst Profiles by year, and whether "Dextromethorphan" was a major or minor topic of these publication.
Bar chart showing 26 publications over 15 distinct years, with a maximum of 3 publications in 1991 and 2001 and 2004 and 2011
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.