"Dextran Sulfate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Long-chain polymer of glucose containing 17-20% sulfur. It has been used as an anticoagulant and also has been shown to inhibit the binding of HIV-1 to CD4-POSITIVE T-LYMPHOCYTES. It is commonly used as both an experimental and clinical laboratory reagent and has been investigated for use as an antiviral agent, in the treatment of hypolipidemia, and for the prevention of free radical damage, among other applications.
Concept/Terms
Dextran Sulfate Sodium- Dextran Sulfate Sodium
- Sulfate Sodium, Dextran
- Sodium Dextran Sulfate
- Dextran Sulfate, Sodium
- Sulfate, Sodium Dextran
Below are MeSH descriptors whose meaning is more general than "Dextran Sulfate".
Below are MeSH descriptors whose meaning is more specific than "Dextran Sulfate".
This graph shows the total number of publications written about "Dextran Sulfate" by people in Harvard Catalyst Profiles by year, and whether "Dextran Sulfate" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1996 | 0 | 3 | 3 |
1997 | 1 | 1 | 2 |
1998 | 1 | 1 | 2 |
1999 | 0 | 1 | 1 |
2000 | 1 | 3 | 4 |
2002 | 0 | 3 | 3 |
2003 | 2 | 1 | 3 |
2004 | 0 | 2 | 2 |
2005 | 1 | 3 | 4 |
2006 | 1 | 1 | 2 |
2007 | 1 | 1 | 2 |
2009 | 1 | 4 | 5 |
2010 | 2 | 7 | 9 |
2011 | 0 | 9 | 9 |
2012 | 0 | 9 | 9 |
2013 | 2 | 7 | 9 |
2014 | 1 | 8 | 9 |
2015 | 2 | 14 | 16 |
2016 | 1 | 6 | 7 |
2017 | 1 | 6 | 7 |
2018 | 0 | 6 | 6 |
2019 | 1 | 13 | 14 |
2020 | 0 | 9 | 9 |
2021 | 1 | 5 | 6 |
2022 | 0 | 5 | 5 |
Below are the most recent publications written about "Dextran Sulfate" by people in Profiles.
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Chronic exposure to synthetic food colorant Allura Red AC promotes susceptibility to experimental colitis via intestinal serotonin in mice. Nat Commun. 2022 12 20; 13(1):7617.
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Siderophore Immunization Restricted Colonization of Adherent-Invasive Escherichia coli and Ameliorated Experimental Colitis. mBio. 2022 10 26; 13(5):e0218422.
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Mechanoscopy: A Novel Device and Procedure for in vivo Detection of Chronic Colitis in Mice. Inflamm Bowel Dis. 2022 08 01; 28(8):1143-1150.
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Enteric glial adenosine 2B receptor signaling mediates persistent epithelial barrier dysfunction following acute DSS colitis. Mucosal Immunol. 2022 05; 15(5):964-976.
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IL-17RA-signaling in Lgr5+ intestinal stem cells induces expression of transcription factor ATOH1 to promote secretory cell lineage commitment. Immunity. 2022 02 08; 55(2):237-253.e8.
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A crosslinked dextran sulfate-chitosan nanoparticle for delivery of therapeutic heparin-binding proteins. Int J Pharm. 2021 Dec 15; 610:121287.
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Experimental Colitis Enhances Temporal Variations in CX3CR1 Cell Colonization of the Gut and Brain Following Irradiation. Am J Pathol. 2022 02; 192(2):295-307.
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Selenium and the 15kDa Selenoprotein Impact Colorectal Tumorigenesis by Modulating Intestinal Barrier Integrity. Int J Mol Sci. 2021 Sep 30; 22(19).
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Saffron Pre-Treatment Promotes Reduction in Tissue Inflammatory Profiles and Alters Microbiome Composition in Experimental Colitis Mice. Molecules. 2021 Jun 02; 26(11).
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Salicylates Ameliorate Intestinal Inflammation by Activating Macrophage AMPK. Inflamm Bowel Dis. 2021 05 17; 27(6):914-926.