Desensitization, Immunologic
"Desensitization, Immunologic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Immunosuppression by the administration of increasing doses of antigen. Though the exact mechanism is not clear, the therapy results in an increase in serum levels of allergen-specific IMMUNOGLOBULIN G, suppression of specific IgE, and an increase in suppressor T-cell activity.
MeSH Number(s)
E02.095.465.425.450.310
E05.478.610.310
Concept/Terms
Desensitization, Immunologic- Desensitization, Immunologic
- Immunologic Desensitization
- Desensitizations, Immunologic
- Immunologic Desensitizations
- Therapy, Hyposensitization
- Hyposensitization Therapies
- Therapies, Hyposensitization
- Hyposensitization Therapy
Allergen Immunotherapy- Allergen Immunotherapy
- Allergen Immunotherapies
- Immunotherapies, Allergen
- Immunotherapy, Allergen
Below are MeSH descriptors whose meaning is more general than "Desensitization, Immunologic".
Below are MeSH descriptors whose meaning is more specific than "Desensitization, Immunologic".
This graph shows the total number of publications written about "Desensitization, Immunologic" by people in Harvard Catalyst Profiles by year, and whether "Desensitization, Immunologic" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 1 | 0 | 1 |
| 1994 | 3 | 1 | 4 |
| 1995 | 3 | 0 | 3 |
| 1996 | 1 | 0 | 1 |
| 1998 | 1 | 0 | 1 |
| 1999 | 2 | 0 | 2 |
| 2000 | 1 | 1 | 2 |
| 2002 | 0 | 1 | 1 |
| 2004 | 4 | 0 | 4 |
| 2005 | 3 | 1 | 4 |
| 2006 | 3 | 0 | 3 |
| 2007 | 1 | 0 | 1 |
| 2008 | 4 | 0 | 4 |
| 2009 | 7 | 1 | 8 |
| 2010 | 7 | 3 | 10 |
| 2011 | 5 | 3 | 8 |
| 2012 | 10 | 2 | 12 |
| 2013 | 6 | 4 | 10 |
| 2014 | 14 | 5 | 19 |
| 2015 | 9 | 7 | 16 |
| 2016 | 15 | 2 | 17 |
| 2017 | 16 | 5 | 21 |
| 2018 | 16 | 5 | 21 |
| 2019 | 16 | 10 | 26 |
| 2020 | 6 | 13 | 19 |
| 2021 | 7 | 10 | 17 |
| 2022 | 4 | 8 | 12 |
| 2023 | 0 | 1 | 1 |
Below are the most recent publications written about "Desensitization, Immunologic" by people in Profiles.
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Immunotherapy-induced neutralizing antibodies disrupt allergen binding and sustain allergen tolerance in peanut allergy. J Clin Invest. 2023 Jan 17; 133(2).
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Utilizing Biologics in Drug Desensitization. Curr Allergy Asthma Rep. 2023 Jan; 23(1):1-11.
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Biomarkers and mechanisms of tolerance induction in food allergic patients drive new therapeutic approaches. Front Immunol. 2022; 13:972103.
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Desensitization in transplantation: is intravenous immunoglobulin the holy grail? J Bras Nefrol. 2022 Oct-Dec; 44(4):470.
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Allergen immunotherapy for atopic dermatitis: Systematic review and meta-analysis of benefits and harms. J Allergy Clin Immunol. 2023 Jan; 151(1):147-158.
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The Case for Prompt Salvage Infant Peanut Oral Immunotherapy Following Failed Primary Prevention. J Allergy Clin Immunol Pract. 2022 10; 10(10):2561-2569.
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Kinetics of basophil hyporesponsiveness during short-course peanut oral immunotherapy. J Allergy Clin Immunol. 2022 Nov; 150(5):1144-1153.
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The Who, What, Where, When, Why, and How of Drug Desensitization. Immunol Allergy Clin North Am. 2022 05; 42(2):403-420.
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Aspirin desensitization and biologics in aspirin-exacerbated respiratory disease: Efficacy, tolerability, and patient experience. Ann Allergy Asthma Immunol. 2022 05; 128(5):575-582.
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Peanut oral immunotherapy differentially suppresses clonally distinct subsets of T helper cells. J Clin Invest. 2022 01 18; 132(2).