Harvard Catalyst Profiles

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Deoxyribonuclease I

"Deoxyribonuclease I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

An enzyme capable of hydrolyzing highly polymerized DNA by splitting phosphodiester linkages, preferentially adjacent to a pyrimidine nucleotide. This catalyzes endonucleolytic cleavage of DNA yielding 5'-phosphodi- and oligonucleotide end-products. The enzyme has a preference for double-stranded DNA.


This graph shows the total number of publications written about "Deoxyribonuclease I" by people in Harvard Catalyst Profiles by year, and whether "Deoxyribonuclease I" was a major or minor topic of these publication.
Bar chart showing 152 publications over 30 distinct years, with a maximum of 10 publications in 2012 and 2013
To see the data from this visualization as text, click here.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.