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Deoxyribonuclease I

"Deoxyribonuclease I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

An enzyme capable of hydrolyzing highly polymerized DNA by splitting phosphodiester linkages, preferentially adjacent to a pyrimidine nucleotide. This catalyzes endonucleolytic cleavage of DNA yielding 5'-phosphodi- and oligonucleotide end-products. The enzyme has a preference for double-stranded DNA.


This graph shows the total number of publications written about "Deoxyribonuclease I" by people in Harvard Catalyst Profiles by year, and whether "Deoxyribonuclease I" was a major or minor topic of these publication.
Bar chart showing 149 publications over 31 distinct years, with a maximum of 11 publications in 2013
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.