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DNA-(Apurinic or Apyrimidinic Site) Lyase

"DNA-(Apurinic or Apyrimidinic Site) Lyase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

A DNA repair enzyme that catalyses the excision of ribose residues at apurinic and apyrimidinic DNA sites that can result from the action of DNA GLYCOSYLASES. The enzyme catalyzes a beta-elimination reaction in which the C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. This enzyme was previously listed under EC

This graph shows the total number of publications written about "DNA-(Apurinic or Apyrimidinic Site) Lyase" by people in Harvard Catalyst Profiles by year, and whether "DNA-(Apurinic or Apyrimidinic Site) Lyase" was a major or minor topic of these publication.
Bar chart showing 49 publications over 21 distinct years, with a maximum of 4 publications in 1998 and 2013 and 2016 and 2017
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.