Harvard Catalyst Profiles

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DNA Topoisomerases, Type I

"DNA Topoisomerases, Type I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

DNA TOPOISOMERASES that catalyze ATP-independent breakage of one of the two strands of DNA, passage of the unbroken strand through the break, and rejoining of the broken strand. DNA Topoisomerases, Type I enzymes reduce the topological stress in the DNA structure by relaxing the superhelical turns and knotted rings in the DNA helix.


This graph shows the total number of publications written about "DNA Topoisomerases, Type I" by people in Harvard Catalyst Profiles by year, and whether "DNA Topoisomerases, Type I" was a major or minor topic of these publication.
Bar chart showing 58 publications over 28 distinct years, with a maximum of 4 publications in 1998
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.