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DNA Topoisomerases

"DNA Topoisomerases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information
Definition  |  Details  |  More General Concepts  |  Related Concepts  |  More Specific Concepts
Enzymes that regulate the topology of DNA by actions such as breaking, relaxing, passing, and rejoining strands of DNA in cells. These enzymes are important components of the DNA replication system. They are classified by their substrate specificities. DNA TOPOISOMERASE I enzymes act on a single strand of DNA. DNA TOPOISOMERASE II enzymes act on double strands of DNA.


publications
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This graph shows the total number of publications written about "DNA Topoisomerases" by people in Harvard Catalyst Profiles by year, and whether "DNA Topoisomerases" was a major or minor topic of these publication.
Bar chart showing 3 publications over 3 distinct years, with a maximum of 1 publications in 2003 and 2015 and 2019
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.