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DNA Repair

"DNA Repair" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

The reconstruction of a continuous two-stranded DNA molecule without mismatch from a molecule which contained damaged regions. The major repair mechanisms are excision repair, in which defective regions in one strand are excised and resynthesized using the complementary base pairing information in the intact strand; photoreactivation repair, in which the lethal and mutagenic effects of ultraviolet light are eliminated; and post-replication repair, in which the primary lesions are not repaired, but the gaps in one daughter duplex are filled in by incorporation of portions of the other (undamaged) daughter duplex. Excision repair and post-replication repair are sometimes referred to as "dark repair" because they do not require light.


This graph shows the total number of publications written about "DNA Repair" by people in Harvard Catalyst Profiles by year, and whether "DNA Repair" was a major or minor topic of these publication.
Bar chart showing 1157 publications over 31 distinct years, with a maximum of 79 publications in 2016
To see the data from this visualization as text, click here.