DNA Breaks, Single-Stranded
"DNA Breaks, Single-Stranded" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Interruptions in one of the strands of the sugar-phosphate backbone of double-stranded DNA.
Concept/Terms
DNA Breaks, Single-Stranded- DNA Breaks, Single-Stranded
- Break, Single-Stranded DNA
- Breaks, Single-Stranded DNA
- DNA Break, Single-Stranded
- DNA Breaks, Single Stranded
- DNA Nicks
- DNA Nick
- Nick, DNA
- Nicks, DNA
- Single-Stranded DNA Break
- Single Stranded DNA Break
- Single-Stranded DNA Breaks
- Single Stranded DNA Breaks
- Single-Strand DNA Breaks
- Break, Single-Strand DNA
- Breaks, Single-Strand DNA
- DNA Break, Single-Strand
- DNA Breaks, Single-Strand
- Single Strand DNA Breaks
- Single-Strand DNA Break
Below are MeSH descriptors whose meaning is more general than "DNA Breaks, Single-Stranded".
Below are MeSH descriptors whose meaning is more specific than "DNA Breaks, Single-Stranded".
This graph shows the total number of publications written about "DNA Breaks, Single-Stranded" by people in Harvard Catalyst Profiles by year, and whether "DNA Breaks, Single-Stranded" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 0 | 1 |
| 2011 | 3 | 0 | 3 |
| 2012 | 3 | 1 | 4 |
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2020 | 0 | 2 | 2 |
| 2021 | 4 | 1 | 5 |
| 2022 | 1 | 0 | 1 |
| 2023 | 0 | 1 | 1 |
Below are the most recent publications written about "DNA Breaks, Single-Stranded" by people in Profiles.
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Role of condensates in modulating DNA repair pathways and its implication for chemoresistance. J Biol Chem. 2023 06; 299(6):104800.
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SPARCLE, a p53-induced lncRNA, controls apoptosis after genotoxic stress by promoting PARP-1 cleavage. Mol Cell. 2022 02 17; 82(4):785-802.e10.
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Temporally distinct post-replicative repair mechanisms fill PRIMPOL-dependent ssDNA gaps in human cells. Mol Cell. 2021 10 07; 81(19):4026-4040.e8.
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Mechanisms of Vertebrate DNA Interstrand Cross-Link Repair. Annu Rev Biochem. 2021 06 20; 90:107-135.
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Neuronal enhancers are hotspots for DNA single-strand break repair. Nature. 2021 05; 593(7859):440-444.
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Single-strand DNA breaks cause replisome disassembly. Mol Cell. 2021 03 18; 81(6):1309-1318.e6.
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CARM1 regulates replication fork speed and stress response by stimulating PARP1. Mol Cell. 2021 02 18; 81(4):784-800.e8.
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Poly (ADP Ribose) Polymerase Inhibitors for Cancer: Essential Biologic, Diagnostic, and Therapeutic Concepts for Today's Practitioner. J Mol Diagn. 2020 09; 22(9):1126-1128.
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An R-loop-initiated CSB-RAD52-POLD3 pathway suppresses ROS-induced telomeric DNA breaks. Nucleic Acids Res. 2020 02 20; 48(3):1285-1300.
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Structural gymnastics of RAG-mediated DNA cleavage in V(D)J recombination. Curr Opin Struct Biol. 2018 12; 53:178-186.