DNA Breaks, Double-Stranded
"DNA Breaks, Double-Stranded" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Interruptions in the sugar-phosphate backbone of DNA, across both strands adjacently.
Concept/Terms
DNA Breaks, Double-Stranded- DNA Breaks, Double-Stranded
- Break, Double-Stranded DNA
- Breaks, Double-Stranded DNA
- DNA Break, Double-Stranded
- DNA Breaks, Double Stranded
- Double-Stranded DNA Break
- Double Stranded DNA Break
- Double-Strand DNA Breaks
- Break, Double-Strand DNA
- Breaks, Double-Strand DNA
- DNA Break, Double-Strand
- DNA Breaks, Double-Strand
- Double Strand DNA Breaks
- Double-Strand DNA Break
- Double-Stranded DNA Breaks
- Double Stranded DNA Breaks
Below are MeSH descriptors whose meaning is more general than "DNA Breaks, Double-Stranded".
Below are MeSH descriptors whose meaning is more specific than "DNA Breaks, Double-Stranded".
This graph shows the total number of publications written about "DNA Breaks, Double-Stranded" by people in Harvard Catalyst Profiles by year, and whether "DNA Breaks, Double-Stranded" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 |
| 2007 | 3 | 3 | 6 |
| 2008 | 9 | 4 | 13 |
| 2009 | 10 | 7 | 17 |
| 2010 | 5 | 10 | 15 |
| 2011 | 9 | 16 | 25 |
| 2012 | 11 | 7 | 18 |
| 2013 | 14 | 16 | 30 |
| 2014 | 15 | 18 | 33 |
| 2015 | 10 | 16 | 26 |
| 2016 | 14 | 15 | 29 |
| 2017 | 15 | 15 | 30 |
| 2018 | 8 | 18 | 26 |
| 2019 | 6 | 17 | 23 |
| 2020 | 14 | 11 | 25 |
| 2021 | 11 | 14 | 25 |
| 2022 | 12 | 7 | 19 |
| 2023 | 6 | 8 | 14 |
Below are the most recent publications written about "DNA Breaks, Double-Stranded" by people in Profiles.
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The RNA m5C modification in R-loops as an off switch of Alt-NHEJ. Nat Commun. 2023 09 30; 14(1):6114.
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An autoinhibited state of 53BP1 revealed by small molecule antagonists and protein engineering. Nat Commun. 2023 09 29; 14(1):6091.
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Neuronal DNA double-strand breaks lead to genome structural variations and 3D genome disruption in neurodegeneration. Cell. 2023 09 28; 186(20):4404-4421.e20.
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Programmable site-specific DNA double-strand breaks via PNA-assisted prokaryotic Argonautes. Nucleic Acids Res. 2023 09 22; 51(17):9491-9506.
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Genome-wide analysis of DNA-PK-bound MRN cleavage products supports a sequential model of DSB repair pathway choice. Nat Commun. 2023 09 16; 14(1):5759.
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Dynamics of the DYNLL1-MRE11 complex regulate DNA end resection and recruitment of Shieldin to DSBs. Nat Struct Mol Biol. 2023 10; 30(10):1456-1467.
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Requirement of WDR70 for POLE3-mediated DNA double-strand breaks repair. Sci Adv. 2023 09 08; 9(36):eadh2358.
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Holding it together: DNA end synapsis during non-homologous end joining. DNA Repair (Amst). 2023 10; 130:103553.
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Therapy-induced APOBEC3A drives evolution of persistent cancer cells. Nature. 2023 Aug; 620(7973):393-401.
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ERa-associated translocations underlie oncogene amplifications in breast cancer. Nature. 2023 Jun; 618(7967):1024-1032.