Cystic Fibrosis Transmembrane Conductance Regulator
"Cystic Fibrosis Transmembrane Conductance Regulator" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A chloride channel that regulates secretion in many exocrine tissues. Abnormalities in the CFTR gene have been shown to cause cystic fibrosis. (Hum Genet 1994;93(4):364-8)
MeSH Number(s)
D12.776.157.530.400.175.125
D12.776.543.550.425.175.125
D12.776.543.585.400.175.125
Below are MeSH descriptors whose meaning is more general than "Cystic Fibrosis Transmembrane Conductance Regulator".
Below are MeSH descriptors whose meaning is more specific than "Cystic Fibrosis Transmembrane Conductance Regulator".
This graph shows the total number of publications written about "Cystic Fibrosis Transmembrane Conductance Regulator" by people in Harvard Catalyst Profiles by year, and whether "Cystic Fibrosis Transmembrane Conductance Regulator" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 0 | 3 | 3 |
| 1994 | 0 | 5 | 5 |
| 1995 | 1 | 2 | 3 |
| 1996 | 5 | 0 | 5 |
| 1997 | 5 | 2 | 7 |
| 1998 | 6 | 1 | 7 |
| 1999 | 6 | 0 | 6 |
| 2000 | 5 | 4 | 9 |
| 2001 | 7 | 3 | 10 |
| 2002 | 7 | 2 | 9 |
| 2003 | 4 | 4 | 8 |
| 2004 | 9 | 5 | 14 |
| 2005 | 5 | 5 | 10 |
| 2006 | 4 | 1 | 5 |
| 2007 | 7 | 3 | 10 |
| 2008 | 4 | 3 | 7 |
| 2009 | 10 | 7 | 17 |
| 2010 | 6 | 7 | 13 |
| 2011 | 8 | 1 | 9 |
| 2012 | 5 | 4 | 9 |
| 2013 | 4 | 2 | 6 |
| 2014 | 6 | 2 | 8 |
| 2015 | 8 | 6 | 14 |
| 2016 | 11 | 5 | 16 |
| 2017 | 12 | 4 | 16 |
| 2018 | 6 | 1 | 7 |
| 2019 | 8 | 7 | 15 |
| 2020 | 7 | 3 | 10 |
| 2021 | 7 | 10 | 17 |
| 2022 | 2 | 13 | 15 |
| 2023 | 2 | 11 | 13 |
Below are the most recent publications written about "Cystic Fibrosis Transmembrane Conductance Regulator" by people in Profiles.
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Inflammatory Activity of Epithelial Stem Cell Variants from Cystic Fibrosis Lungs Is Not Resolved by CFTR Modulators. Am J Respir Crit Care Med. 2023 11 01; 208(9):930-943.
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Transgenic ferret models define pulmonary ionocyte diversity and function. Nature. 2023 Sep; 621(7980):857-867.
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Cystic Fibrosis: "Ionocyte Modulators"? Am J Respir Cell Mol Biol. 2023 09; 69(3):250-252.
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CFTR Modulators for the Gastroenterologist. J Pediatr Gastroenterol Nutr. 2023 10 01; 77(4):445-447.
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Positive and negative impacts of elexacaftor/tezacaftor/ivacaftor: Healthcare providers' observations across US centers. Pediatr Pulmonol. 2023 09; 58(9):2469-2477.
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Cystic Fibrosis-Related Diabetes Workshop: Research Priorities Spanning Disease Pathophysiology, Diagnosis, and Outcomes. Diabetes. 2023 06 01; 72(6):677-689.
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Cystic Fibrosis-Related Diabetes Workshop: Research Priorities Spanning Disease Pathophysiology, Diagnosis, and Outcomes. Diabetes Care. 2023 06 01; 46(6):1112-1123.
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Engineered tRNAs suppress nonsense mutations in cells and in vivo. Nature. 2023 Jun; 618(7966):842-848.
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Who Modifies the Modifiers: A High-Resolution View of the Genetic Modifiers of Cystic Fibrosis. Am J Respir Crit Care Med. 2023 05 15; 207(10):1261-1262.
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De Novo Generation of Pulmonary Ionocytes from Normal and Cystic Fibrosis Human Induced Pluripotent Stem Cells. Am J Respir Crit Care Med. 2023 05 01; 207(9):1249-1253.