Cysteine Dioxygenase

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"Cysteine Dioxygenase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

An enzyme that catalyzes the conversion of L-CYSTEINE to 3-sulfinoalanine (3-sulfino-L-alanine) in the CYSTEINE metabolism and TAURINE and hypotaurine metabolic pathways.

Descriptor ID

D050558

MeSH Number(s)

D08.811.682.690.416.319

Concept/Terms

Cysteine Dioxygenase

Below are MeSH descriptors whose meaning is more general than "Cysteine Dioxygenase".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Oxidoreductases [D08.811.682]
Oxygenases [D08.811.682.690]
Dioxygenases [D08.811.682.690.416]
Cysteine Dioxygenase [D08.811.682.690.416.319]

Below are MeSH descriptors whose meaning is related to "Cysteine Dioxygenase".

Below are MeSH descriptors whose meaning is more specific than "Cysteine Dioxygenase".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Cysteine Dioxygenase" by people in Harvard Catalyst Profiles by year, and whether "Cysteine Dioxygenase" was a major or minor topic of these publication.

To see the data from this visualization as text, click here.

Below are the most recent publications written about "Cysteine Dioxygenase" by people in Profiles.

Stipanuk MH, Simmons CR, Karplus PA, Dominy JE. Thiol dioxygenases: unique families of cupin proteins. Amino Acids. 2011 Jun; 41(1):91-102.

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Simmons CR, Krishnamoorthy K, Granett SL, Schuller DJ, Dominy JE, Begley TP, Stipanuk MH, Karplus PA. A putative Fe2+-bound persulfenate intermediate in cysteine dioxygenase. Biochemistry. 2008 Nov 04; 47(44):11390-2.

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Dominy JE, Hwang J, Guo S, Hirschberger LL, Zhang S, Stipanuk MH. Synthesis of amino acid cofactor in cysteine dioxygenase is regulated by substrate and represents a novel post-translational regulation of activity. J Biol Chem. 2008 May 02; 283(18):12188-201.

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Dominy JE, Simmons CR, Hirschberger LL, Hwang J, Coloso RM, Stipanuk MH. Discovery and characterization of a second mammalian thiol dioxygenase, cysteamine dioxygenase. J Biol Chem. 2007 Aug 31; 282(35):25189-98.

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Dominy JE, Hwang J, Stipanuk MH. Overexpression of cysteine dioxygenase reduces intracellular cysteine and glutathione pools in HepG2/C3A cells. Am J Physiol Endocrinol Metab. 2007 Jul; 293(1):E62-9.

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Dominy JE, Simmons CR, Karplus PA, Gehring AM, Stipanuk MH. Identification and characterization of bacterial cysteine dioxygenases: a new route of cysteine degradation for eubacteria. J Bacteriol. 2006 Aug; 188(15):5561-9.

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Stipanuk MH, Dominy JE, Lee JI, Coloso RM. Mammalian cysteine metabolism: new insights into regulation of cysteine metabolism. J Nutr. 2006 06; 136(6 Suppl):1652S-1659S.

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Dominy JE, Hirschberger LL, Coloso RM, Stipanuk MH. Regulation of cysteine dioxygenase degradation is mediated by intracellular cysteine levels and the ubiquitin-26 S proteasome system in the living rat. Biochem J. 2006 Feb 15; 394(Pt 1):267-73.

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Dominy JE, Hirschberger LL, Coloso RM, Stipanuk MH. In vivo regulation of cysteine dioxygenase via the ubiquitin-26S proteasome system. Adv Exp Med Biol. 2006; 583:37-47.

View in: PubMed

Related Networks

Top Journals

J Biol Chem
J Bacteriol
Biochemistry
Biochem J
Amino Acids
Am J Physiol Endocrinol Metab
Adv Exp Med Biol
J Nutr

Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana-Farber Cancer Institute.

Cysteine Dioxygenase

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