"Cyclophilin A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 17-KDa cytoplasmic PEPTIDYLPROLYL ISOMERASE involved in immunoregulation. It is a member of the cyclophilin family of proteins that binds to CYCLOSPORINE.
MeSH Number(s)
D08.811.399.325.500.400.300.500
Concept/Terms
Cyclophilin A- Cyclophilin A
- A, Cyclophilin
- Peptidyl-Prolyl cis-trans Isomerase A
Below are MeSH descriptors whose meaning is more general than "Cyclophilin A".
Below are MeSH descriptors whose meaning is more specific than "Cyclophilin A".
This graph shows the total number of publications written about "Cyclophilin A" by people in Harvard Catalyst Profiles by year, and whether "Cyclophilin A" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 1 | 1 | 2 |
| 2002 | 1 | 0 | 1 |
| 2004 | 1 | 1 | 2 |
| 2006 | 2 | 1 | 3 |
| 2007 | 1 | 1 | 2 |
| 2008 | 2 | 0 | 2 |
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 2 | 3 |
| 2011 | 1 | 0 | 1 |
| 2012 | 4 | 0 | 4 |
| 2013 | 1 | 1 | 2 |
| 2014 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 2 | 1 | 3 |
| 2017 | 1 | 1 | 2 |
| 2018 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 2 | 0 | 2 |
| 2023 | 0 | 1 | 1 |
Below are the most recent publications written about "Cyclophilin A" by people in Profiles.
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In vivo bone marrow microenvironment siRNA delivery using lipid-polymer nanoparticles for multiple myeloma therapy. Proc Natl Acad Sci U S A. 2023 06 20; 120(25):e2215711120.
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CD147-Cyclophilin a Interactions Promote Proliferation and Survival of Cutaneous T-Cell Lymphoma. Int J Mol Sci. 2021 Jul 23; 22(15).
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Cytoplasmic CPSF6 Regulates HIV-1 Capsid Trafficking and Infection in a Cyclophilin A-Dependent Manner. mBio. 2021 03 23; 12(2).
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Intrinsic curvature of the HIV-1 CA hexamer underlies capsid topology and interaction with cyclophilin A. Nat Struct Mol Biol. 2020 09; 27(9):855-862.
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A novel elastin-like polypeptide drug carrier for cyclosporine A improves tear flow in a mouse model of Sjögren's syndrome. J Control Release. 2018 12 28; 292:183-195.
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Potent and reversible lentiviral vector restriction in murine induced pluripotent stem cells. Retrovirology. 2017 05 31; 14(1):34.
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IMPDH2 Is an Intracellular Target of the Cyclophilin A and Sanglifehrin A Complex. Cell Rep. 2017 01 10; 18(2):432-442.
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Association of Polymorphisms in the Regulatory Region of the Cyclophilin a Gene (PPIA) with Gene Expression and HIV/AIDS Disease Progression. J Acquir Immune Defic Syndr. 2016 08 15; 72(5):465-73.
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Roles of Capsid-Interacting Host Factors in Multimodal Inhibition of HIV-1 by PF74. J Virol. 2016 06 15; 90(12):5808-5823.
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Cyclophilin A stabilizes the HIV-1 capsid through a novel non-canonical binding site. Nat Commun. 2016 Mar 04; 7:10714.