"Cyclooxygenase 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An inducibly-expressed subtype of prostaglandin-endoperoxide synthase. It plays an important role in many cellular processes and INFLAMMATION. It is the target of COX2 INHIBITORS.
Concept/Terms
Cyclooxygenase 2- Cyclooxygenase 2
- Cyclo-Oxygenase II
- Cyclo Oxygenase II
- PTGS2
- PGHS-2
- Prostaglandin H Synthase-2
- Prostaglandin H Synthase 2
- COX-2 Prostaglandin Synthase
- COX 2 Prostaglandin Synthase
- Prostaglandin Synthase, COX-2
- Synthase, COX-2 Prostaglandin
- Cyclooxygenase-2
Below are MeSH descriptors whose meaning is more general than "Cyclooxygenase 2".
Below are MeSH descriptors whose meaning is more specific than "Cyclooxygenase 2".
This graph shows the total number of publications written about "Cyclooxygenase 2" by people in Harvard Catalyst Profiles by year, and whether "Cyclooxygenase 2" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 5 | 5 |
| 1997 | 0 | 5 | 5 |
| 1998 | 0 | 7 | 7 |
| 1999 | 0 | 16 | 16 |
| 2000 | 0 | 18 | 18 |
| 2001 | 0 | 14 | 14 |
| 2002 | 0 | 21 | 21 |
| 2003 | 0 | 32 | 32 |
| 2004 | 0 | 36 | 36 |
| 2005 | 6 | 21 | 27 |
| 2006 | 11 | 10 | 21 |
| 2007 | 10 | 6 | 16 |
| 2008 | 13 | 3 | 16 |
| 2009 | 15 | 7 | 22 |
| 2010 | 6 | 11 | 17 |
| 2011 | 7 | 8 | 15 |
| 2012 | 4 | 11 | 15 |
| 2013 | 3 | 14 | 17 |
| 2014 | 4 | 8 | 12 |
| 2015 | 5 | 14 | 19 |
| 2016 | 5 | 6 | 11 |
| 2017 | 4 | 8 | 12 |
| 2018 | 5 | 7 | 12 |
| 2019 | 5 | 6 | 11 |
| 2020 | 3 | 4 | 7 |
| 2021 | 1 | 4 | 5 |
| 2022 | 0 | 4 | 4 |
Below are the most recent publications written about "Cyclooxygenase 2" by people in Profiles.
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Associations of aspirin and other anti-inflammatory medications with breast cancer risk by the status of COX-2 expression. Breast Cancer Res. 2022 12 09; 24(1):89.
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Phytochemical Combination Is More Effective than Individual Components in Reducing Stress Signaling in Rat Hippocampal Neurons and Microglia In Vitro. Int J Mol Sci. 2022 Oct 21; 23(20).
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Resolvin E1 Reduces Tumor Growth in a Xenograft Model of Lung Cancer. Am J Pathol. 2022 Oct; 192(10):1470-1484.
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Staphylococcus aureus controls eicosanoid and specialized pro-resolving mediator production via lipoteichoic acid. Immunology. 2022 05; 166(1):47-67.
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The Fusion Protein rFlaA:Betv1 Modulates DC Responses by a p38-MAPK and COX2-Dependent Secretion of PGE2 from Epithelial Cells. Cells. 2021 12 04; 10(12).
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The cardiac molecular setting of metabolic syndrome in pigs reveals disease susceptibility and suggests mechanisms that exacerbate COVID-19 outcomes in patients. Sci Rep. 2021 10 05; 11(1):19752.
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Radiation-Induced Macrophage Senescence Impairs Resolution Programs and Drives Cardiovascular Inflammation. J Immunol. 2021 10 01; 207(7):1812-1823.
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Ergosta-7,9(11),22-trien-3ß-ol Alleviates Intracerebral Hemorrhage-Induced Brain Injury and BV-2 Microglial Activation. Molecules. 2021 May 17; 26(10).
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Combination of EP4 antagonist MF-766 and anti-PD-1 promotes anti-tumor efficacy by modulating both lymphocytes and myeloid cells. Oncoimmunology. 2021 03 18; 10(1):1896643.
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The transcription factor NRF2 enhances melanoma malignancy by blocking differentiation and inducing COX2 expression. Oncogene. 2020 10; 39(44):6841-6855.