Complement Pathway, Mannose-Binding Lectin
"Complement Pathway, Mannose-Binding Lectin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Complement activation triggered by the interaction of microbial POLYSACCHARIDES with serum MANNOSE-BINDING LECTIN resulting in the activation of MANNOSE-BINDING PROTEIN-ASSOCIATED SERINE PROTEASES. As in the classical pathway, MASPs cleave COMPLEMENT C4 and COMPLEMENT C2 to form C3 CONVERTASE (C4B2A) and the subsequent C5 CONVERTASE (C4B2A3B) leading to cleavage of COMPLEMENT C5 and assembly of COMPLEMENT MEMBRANE ATTACK COMPLEX.
Concept/Terms
Complement Pathway, Mannose-Binding Lectin- Complement Pathway, Mannose-Binding Lectin
- Complement Pathway, Mannose Binding Lectin
- Lectin-Complement Pathway
- Lectin Complement Pathway
- Lectin-Complement Pathways
- Pathway, Lectin-Complement
- Pathways, Lectin-Complement
- Mannan-Binding Lectin Complement Pathway
- Mannan Binding Lectin Complement Pathway
- Mannose-Binding Lectin Complement Pathway
- Mannose Binding Lectin Complement Pathway
- Mannan-Binding Lectin Pathway (Complement Activation)
- Lectin Pathway, Mannan-Binding (Complement Activation)
- Lectin Pathways, Mannan-Binding (Complement Activation)
- Mannan Binding Lectin Pathway (Complement Activation)
- Mannan-Binding Lectin Pathways (Complement Activation)
- Pathway, Mannan-Binding Lectin (Complement Activation)
- Pathways, Mannan-Binding Lectin (Complement Activation)
Below are MeSH descriptors whose meaning is more general than "Complement Pathway, Mannose-Binding Lectin".
Below are MeSH descriptors whose meaning is more specific than "Complement Pathway, Mannose-Binding Lectin".
This graph shows the total number of publications written about "Complement Pathway, Mannose-Binding Lectin" by people in Harvard Catalyst Profiles by year, and whether "Complement Pathway, Mannose-Binding Lectin" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 2 | 3 |
| 2006 | 3 | 0 | 3 |
| 2007 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 2 | 3 |
| 2011 | 3 | 1 | 4 |
| 2012 | 0 | 1 | 1 |
| 2014 | 1 | 1 | 2 |
| 2019 | 1 | 0 | 1 |
Below are the most recent publications written about "Complement Pathway, Mannose-Binding Lectin" by people in Profiles.
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Thiol isomerase ERp57 targets and modulates the lectin pathway of complement activation. J Biol Chem. 2019 03 29; 294(13):4878-4888.
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MASP-3 is the exclusive pro-factor D activator in resting blood: the lectin and the alternative complement pathways are fundamentally linked. Sci Rep. 2016 08 18; 6:31877.
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Complement blockade with a C1 esterase inhibitor in paroxysmal nocturnal hemoglobinuria. Exp Hematol. 2014 Oct; 42(10):857-61.e1.
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Analysis of the complement activation in mice. Methods Mol Biol. 2014; 1100:365-71.
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The role of complement in membranous nephropathy. Semin Nephrol. 2013 Nov; 33(6):531-42.
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Endogenous and natural complement inhibitor attenuates myocardial injury and arterial thrombogenesis. Circulation. 2012 Oct 30; 126(18):2227-35.
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The alternative complement pathway propagates inflammation and injury in murine ischemic stroke. J Immunol. 2012 Nov 01; 189(9):4640-7.
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Mannose-binding lectin-associated serine protease-1 is a significant contributor to coagulation in a murine model of occlusive thrombosis. J Immunol. 2012 Jan 15; 188(2):885-91.
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Mannose-binding lectin and the balance between immune protection and complication. Expert Rev Anti Infect Ther. 2011 Dec; 9(12):1179-90.
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In vitro C3 deposition on Cryptococcus capsule occurs via multiple complement activation pathways. Mol Immunol. 2011 Sep; 48(15-16):2009-18.