Harvard Catalyst Profiles

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Complement Membrane Attack Complex

"Complement Membrane Attack Complex" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

A product of COMPLEMENT ACTIVATION cascade, regardless of the pathways, that forms transmembrane channels causing disruption of the target CELL MEMBRANE and cell lysis. It is formed by the sequential assembly of terminal complement components (COMPLEMENT C5B; COMPLEMENT C6; COMPLEMENT C7; COMPLEMENT C8; and COMPLEMENT C9) into the target membrane. The resultant C5b-8-poly-C9 is the "membrane attack complex" or MAC.


This graph shows the total number of publications written about "Complement Membrane Attack Complex" by people in Harvard Catalyst Profiles by year, and whether "Complement Membrane Attack Complex" was a major or minor topic of these publication.
Bar chart showing 63 publications over 25 distinct years, with a maximum of 6 publications in 1993 and 1999 and 2009
To see the data from this visualization as text, click here.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.