Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Complement C3

"Complement C3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

A glycoprotein that is central in both the classical and the alternative pathway of COMPLEMENT ACTIVATION. C3 can be cleaved into COMPLEMENT C3A and COMPLEMENT C3B, spontaneously at low level or by C3 CONVERTASE at high level. The smaller fragment C3a is an ANAPHYLATOXIN and mediator of local inflammatory process. The larger fragment C3b binds with C3 convertase to form C5 convertase.


This graph shows the total number of publications written about "Complement C3" by people in Harvard Catalyst Profiles by year, and whether "Complement C3" was a major or minor topic of these publication.
Bar chart showing 207 publications over 30 distinct years, with a maximum of 15 publications in 2008
To see the data from this visualization as text, click here.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.