Combinatorial Chemistry Techniques
"Combinatorial Chemistry Techniques" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A technology, in which sets of reactions for solution or solid-phase synthesis, is used to create molecular libraries for analysis of compounds on a large scale.
MeSH Number(s)
E05.916.039.312
G02.607.750.155.249
J01.897.836.249.249
Concept/Terms
Combinatorial Chemistry Techniques- Combinatorial Chemistry Techniques
- Chemistry Technics, Combinatorial
- Chemistry Technique, Combinatorial
- Chemistry Techniques, Combinatorial
- Techniques, Combinatorial Chemistry
- Combinatorial Chemistry Technics
- Combinatorial Chemistry Technique
- Technic, Combinatorial Chemistry
- Technics, Combinatorial Chemistry
- Technique, Combinatorial Chemistry
- Chemistry Technic, Combinatorial
- Combinatorial Chemistry Technic
Below are MeSH descriptors whose meaning is more general than "Combinatorial Chemistry Techniques".
Below are MeSH descriptors whose meaning is more specific than "Combinatorial Chemistry Techniques".
This graph shows the total number of publications written about "Combinatorial Chemistry Techniques" by people in Harvard Catalyst Profiles by year, and whether "Combinatorial Chemistry Techniques" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2000 | 2 | 4 | 6 |
| 2001 | 5 | 5 | 10 |
| 2002 | 2 | 4 | 6 |
| 2003 | 5 | 7 | 12 |
| 2004 | 1 | 6 | 7 |
| 2005 | 2 | 4 | 6 |
| 2006 | 1 | 1 | 2 |
| 2007 | 4 | 0 | 4 |
| 2008 | 2 | 6 | 8 |
| 2009 | 5 | 4 | 9 |
| 2010 | 5 | 3 | 8 |
| 2011 | 6 | 0 | 6 |
| 2012 | 2 | 1 | 3 |
| 2013 | 1 | 3 | 4 |
| 2014 | 1 | 1 | 2 |
| 2015 | 0 | 5 | 5 |
| 2016 | 1 | 2 | 3 |
| 2018 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
Below are the most recent publications written about "Combinatorial Chemistry Techniques" by people in Profiles.
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Droplet-based combinatorial indexing for massive-scale single-cell chromatin accessibility. Nat Biotechnol. 2019 08; 37(8):916-924.
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Gradient platform for combinatorial screening of thermoset polymers for biomedical applications. Mater Sci Eng C Mater Biol Appl. 2019 Jan 01; 94:766-777.
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Xenoprotein engineering via synthetic libraries. Proc Natl Acad Sci U S A. 2018 06 05; 115(23):E5298-E5306.
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Target-directed Dynamic Combinatorial Chemistry: A Study on Potentials and Pitfalls as Exemplified on a Bacterial Target. Chemistry. 2017 Aug 25; 23(48):11570-11577.
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Portable, On-Demand Biomolecular Manufacturing. Cell. 2016 Sep 22; 167(1):248-259.e12.
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Design of a Microfluidic Chip for Magnetic-Activated Sorting of One-Bead-One-Compound Libraries. ACS Comb Sci. 2016 06 13; 18(6):271-8.
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Big insights from small volumes: deciphering complex leukocyte behaviors using microfluidics. J Leukoc Biol. 2016 08; 100(2):291-304.
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A defined synthetic substrate for serum-free culture of human stem cell derived cardiomyocytes with improved functional maturity identified using combinatorial materials microarrays. Biomaterials. 2015 Aug; 61:257-65.
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High-Throughput Sorting and Placement of One-Bead-One-Compound (OBOC) Libraries from Bulk to Single Wells in Organic Solvent. ACS Comb Sci. 2015 May 11; 17(5):303-9.
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Compounds targeting disulfide bond forming enzyme DsbB of Gram-negative bacteria. Nat Chem Biol. 2015 Apr; 11(4):292-8.