Clotrimazole

"Clotrimazole" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

An imidazole derivative with a broad spectrum of antimycotic activity. It inhibits biosynthesis of the sterol ergostol, an important component of fungal CELL MEMBRANES. Its action leads to increased membrane permeability and apparent disruption of enzyme systems bound to the membrane.

Descriptor ID

D003022

MeSH Number(s)

D03.383.129.308.175

Concept/Terms

Below are MeSH descriptors whose meaning is more general than "Clotrimazole".

Chemicals and Drugs [D]
Heterocyclic Compounds [D03]
Heterocyclic Compounds, 1-Ring [D03.383]
Azoles [D03.383.129]
Imidazoles [D03.383.129.308]
Clotrimazole [D03.383.129.308.175]

Below are MeSH descriptors whose meaning is more specific than "Clotrimazole".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Clotrimazole" by people in Harvard Catalyst Profiles by year, and whether "Clotrimazole" was a major or minor topic of these publication.

Bar chart showing 39 publications over 19 distinct years, with a maximum of 8 publications in 1995

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	1	0	1
1995	7	1	8
1996	4	1	5
1997	3	1	4
1998	2	1	3
1999	1	3	4
2000	0	1	1
2001	0	1	1
2002	0	1	1
2004	1	0	1
2005	0	1	1
2006	0	1	1
2008	0	1	1
2011	1	1	2
2012	1	0	1
2013	1	0	1
2015	1	0	1
2016	0	1	1
2019	0	1	1

Below are the most recent publications written about "Clotrimazole" by people in Profiles.

Intestinal epithelial potassium channels and CFTR chloride channels activated in ErbB tyrosine kinase inhibitor diarrhea. JCI Insight. 2019 02 21; 4(4).

View in: PubMed
Oral candidiasis following steroid therapy for oral lichen planus. Oral Dis. 2016 Mar; 22(2):140-7.

View in: PubMed
Electrophysiological Studies into the Safety of the Anti-diarrheal Drug Clotrimazole during Oral Rehydration Therapy. PLoS Negl Trop Dis. 2015 Sep; 9(9):e0004098.

View in: PubMed
Small-Molecule targeting of translation initiation for cancer therapy. Oncotarget. 2013 Oct; 4(10):1606-17.

View in: PubMed
Optimization of 4-aminoquinoline/clotrimazole-based hybrid antimalarials: further structure-activity relationships, in vivo studies, and preliminary toxicity profiling. J Med Chem. 2012 Aug 09; 55(15):6948-67.

View in: PubMed
Aldolase mRNA expression in endometrial cancer and the role of clotrimazole in endometrial cancer cell viability and morphology. Histopathology. 2011 Nov; 59(5):1015-8.

View in: PubMed
Novel high-throughput screen against Candida albicans identifies antifungal potentiators and agents effective against biofilms. J Antimicrob Chemother. 2011 Apr; 66(4):820-6.

View in: PubMed
Median rhomboid glossitis. J Mass Dent Soc. 2011; 59(4):41.

View in: PubMed
Azole drugs trap cytochrome P450 EryK in alternative conformational states. Biochemistry. 2010 Nov 02; 49(43):9199-206.

View in: PubMed
Inhibitory effects of clotrimazole on TNF-alpha-induced adhesion molecule expression and angiogenesis. Arch Pharm Res. 2009 Apr; 32(4):593-603.

View in: PubMed

Related Networks

People

Explore

Similar Concepts

Top Journals

J Clin Invest
Blood
J Pharmacol Exp Ther
Ann N Y Acad Sci
Biochem Pharmacol
Arterioscler Thromb Vasc Biol
Arch Pharm Res
Arch Dermatol Res
Am J Physiol
Am J Med