"Clodronic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A diphosphonate which affects calcium metabolism. It inhibits bone resorption and soft tissue calcification.
Concept/Terms
Clodronic Acid- Clodronic Acid
- Acid, Clodronic
- Dichloromethane Diphosphonate
- Diphosphonate, Dichloromethane
- Dichloromethylenebisphosphonate
- Dichloromethanediphosphonic Acid
- Acid, Dichloromethanediphosphonic
- Dichloromethylene Biphosphonate
- Biphosphonate, Dichloromethylene
- Dichloromethylene Diphosphonate
- Diphosphonate, Dichloromethylene
- Cl2MDP
- Dichloromethanediphosphonate
Below are MeSH descriptors whose meaning is more general than "Clodronic Acid".
Below are MeSH descriptors whose meaning is more specific than "Clodronic Acid".
This graph shows the total number of publications written about "Clodronic Acid" by people in Harvard Catalyst Profiles by year, and whether "Clodronic Acid" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 2 | 0 | 2 |
| 1994 | 1 | 1 | 2 |
| 1996 | 1 | 0 | 1 |
| 1998 | 1 | 1 | 2 |
| 1999 | 1 | 0 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 1 | 2 | 3 |
| 2003 | 0 | 2 | 2 |
| 2004 | 1 | 0 | 1 |
| 2005 | 0 | 1 | 1 |
| 2008 | 1 | 1 | 2 |
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 1 | 2 |
| 2011 | 1 | 1 | 2 |
| 2012 | 0 | 3 | 3 |
| 2013 | 0 | 4 | 4 |
| 2014 | 0 | 2 | 2 |
| 2015 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2019 | 1 | 1 | 2 |
Below are the most recent publications written about "Clodronic Acid" by people in Profiles.
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Versatile cell ablation tools and their applications to study loss of cell functions. Cell Mol Life Sci. 2019 Dec; 76(23):4725-4743.
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Depletion and Reconstitution of Macrophages in Mice. Methods Mol Biol. 2019; 1960:101-112.
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Hematopoietic stem cell loss and hematopoietic failure in severe aplastic anemia is driven by macrophages and aberrant podoplanin expression. Haematologica. 2018 09; 103(9):1451-1461.
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Use of Adjuvant Bisphosphonates and Other Bone-Modifying Agents in Breast Cancer: A Cancer Care Ontario and American Society of Clinical Oncology Clinical Practice Guideline. J Clin Oncol. 2017 Jun 20; 35(18):2062-2081.
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Targeting Macrophages Sensitizes Chronic Lymphocytic Leukemia to Apoptosis and Inhibits Disease Progression. Cell Rep. 2016 Feb 23; 14(7):1748-1760.
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Macrophage recruitment by fibrocystin-defective biliary epithelial cells promotes portal fibrosis in congenital hepatic fibrosis. Hepatology. 2016 Mar; 63(3):965-82.
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LKB1 loss promotes endometrial cancer progression via CCL2-dependent macrophage recruitment. J Clin Invest. 2015 Nov 02; 125(11):4063-76.
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Pentoxifylline-tocopherol-clodronate combination: A novel treatment for osteoradionecrosis of the temporal bone. Head Neck. 2015 Dec; 37(12):E191-3.
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Aberrant actin depolymerization triggers the pyrin inflammasome and autoinflammatory disease that is dependent on IL-18, not IL-1ß. J Exp Med. 2015 Jun 01; 212(6):927-38.
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Neutrophils mediate airway hyperresponsiveness after chlorine-induced airway injury in the mouse. Am J Respir Cell Mol Biol. 2015 Apr; 52(4):513-22.