Harvard Catalyst Profiles

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Click Chemistry

"Click Chemistry" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

Organic chemistry methodology that mimics the modular nature of various biosynthetic processes. It uses highly reliable and selective reactions designed to "click" i.e., rapidly join small modular units together in high yield, without offensive byproducts. In combination with COMBINATORIAL CHEMISTRY TECHNIQUES, it is used for the synthesis of new compounds and combinatorial libraries.

This graph shows the total number of publications written about "Click Chemistry" by people in Harvard Catalyst Profiles by year, and whether "Click Chemistry" was a major or minor topic of these publication.
Bar chart showing 76 publications over 14 distinct years, with a maximum of 9 publications in 2014 and 2015 and 2018 and 2019
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.