Chromosomes, Artificial, Yeast
"Chromosomes, Artificial, Yeast" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Chromosomes in which fragments of exogenous DNA ranging in length up to several hundred kilobase pairs have been cloned into yeast through ligation to vector sequences. These artificial chromosomes are used extensively in molecular biology for the construction of comprehensive genomic libraries of higher organisms.
MeSH Number(s)
A11.284.187.178.200
A11.284.187.360.800
A19.311.800
G05.360.162.178.200
G05.360.162.360.800
G05.360.337.249.200
Concept/Terms
Chromosomes, Artificial, Yeast- Chromosomes, Artificial, Yeast
- Chromosomes, Yeast Artificial
- YACs (Chromosomes)
- YAC (Chromosome)
- Yeast Artificial Chromosomes
- Artificial Chromosomes, Yeast
- Artificial Chromosome, Yeast
- Chromosome, Yeast Artificial
- Yeast Artificial Chromosome
Below are MeSH descriptors whose meaning is more general than "Chromosomes, Artificial, Yeast".
- Anatomy [A]
- Cells [A11]
- Cellular Structures [A11.284]
- Chromosomes [A11.284.187]
- Chromosomes, Artificial [A11.284.187.178]
- Chromosomes, Artificial, Yeast [A11.284.187.178.200]
- Chromosomes, Fungal [A11.284.187.360]
- Chromosomes, Artificial, Yeast [A11.284.187.360.800]
- Fungal Structures [A19]
- Chromosomes, Fungal [A19.311]
- Chromosomes, Artificial, Yeast [A19.311.800]
- Biological Sciences [G]
- Genetic Phenomena [G05]
- Genetic Structures [G05.360]
- Chromosomes [G05.360.162]
- Chromosomes, Artificial [G05.360.162.178]
- Chromosomes, Artificial, Yeast [G05.360.162.178.200]
- Chromosomes, Fungal [G05.360.162.360]
- Chromosomes, Artificial, Yeast [G05.360.162.360.800]
- Genetic Vectors [G05.360.337]
- Chromosomes, Artificial [G05.360.337.249]
- Chromosomes, Artificial, Yeast [G05.360.337.249.200]
Below are MeSH descriptors whose meaning is more specific than "Chromosomes, Artificial, Yeast".
This graph shows the total number of publications written about "Chromosomes, Artificial, Yeast" by people in Harvard Catalyst Profiles by year, and whether "Chromosomes, Artificial, Yeast" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 0 | 2 | 2 |
| 1994 | 2 | 6 | 8 |
| 1995 | 5 | 16 | 21 |
| 1996 | 1 | 12 | 13 |
| 1997 | 1 | 16 | 17 |
| 1998 | 0 | 6 | 6 |
| 1999 | 2 | 10 | 12 |
| 2000 | 0 | 3 | 3 |
| 2001 | 0 | 6 | 6 |
| 2002 | 0 | 1 | 1 |
| 2004 | 1 | 1 | 2 |
| 2007 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
Below are the most recent publications written about "Chromosomes, Artificial, Yeast" by people in Profiles.
-
Design of a synthetic yeast genome. Science. 2017 03 10; 355(6329):1040-1044.
-
Aneuploid yeast strains exhibit defects in cell growth and passage through START. Mol Biol Cell. 2013 May; 24(9):1274-89.
-
A functional evolutionary approach to identify determinants of nucleosome positioning: a unifying model for establishing the genome-wide pattern. Mol Cell. 2012 Oct 12; 48(1):5-15.
-
RNase H and multiple RNA biogenesis factors cooperate to prevent RNA:DNA hybrids from generating genome instability. Mol Cell. 2011 Dec 23; 44(6):978-88.
-
The hAPP-YAC transgenic model has elevated UPS activity in the frontal cortex similar to Alzheimer's disease and Down's syndrome. J Neurochem. 2010 Sep; 114(6):1819-26.
-
Balance between synaptic versus extrasynaptic NMDA receptor activity influences inclusions and neurotoxicity of mutant huntingtin. Nat Med. 2009 Dec; 15(12):1407-13.
-
Age-dependent alterations of corticostriatal activity in the YAC128 mouse model of Huntington disease. J Neurosci. 2009 Feb 25; 29(8):2414-27.
-
Cholesterol biosynthesis pathway is disturbed in YAC128 mice and is modulated by huntingtin mutation. Hum Mol Genet. 2007 Sep 15; 16(18):2187-98.
-
Glutamate receptor abnormalities in the YAC128 transgenic mouse model of Huntington's disease. Neuroscience. 2007 Jun 29; 147(2):354-72.
-
A Gata2 intronic enhancer confers its pan-endothelia-specific regulation. Development. 2007 May; 134(9):1703-12.