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Cholesterol Side-Chain Cleavage Enzyme

"Cholesterol Side-Chain Cleavage Enzyme" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

A mitochondrial cytochrome P450 enzyme that catalyzes the side-chain cleavage of C27 cholesterol to C21 pregnenolone in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP11A1 gene, catalyzes the breakage between C20 and C22 which is the initial and rate-limiting step in the biosynthesis of various gonadal and adrenal steroid hormones.


This graph shows the total number of publications written about "Cholesterol Side-Chain Cleavage Enzyme" by people in Harvard Catalyst Profiles by year, and whether "Cholesterol Side-Chain Cleavage Enzyme" was a major or minor topic of these publication.
Bar chart showing 16 publications over 13 distinct years, with a maximum of 2 publications in 1996 and 2017 and 2019
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.