Harvard Catalyst Profiles

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Chediak-Higashi Syndrome

"Chediak-Higashi Syndrome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

A form of phagocyte bactericidal dysfunction characterized by unusual oculocutaneous albinism, high incidence of lymphoreticular neoplasms, and recurrent pyogenic infections. In many cell types, abnormal lysosomes are present leading to defective pigment distribution and abnormal neutrophil functions. The disease is transmitted by autosomal recessive inheritance and a similar disorder occurs in the beige mouse, the Aleutian mink, and albino Hereford cattle.


This graph shows the total number of publications written about "Chediak-Higashi Syndrome" by people in Harvard Catalyst Profiles by year, and whether "Chediak-Higashi Syndrome" was a major or minor topic of these publication.
Bar chart showing 4 publications over 4 distinct years, with a maximum of 1 publications in 1992 and 1993 and 1994 and 2009
To see the data from this visualization as text, click here.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.