Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Caspase 8

"Caspase 8" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

A long pro-domain caspase that contains a death effector domain in its pro-domain region. Caspase 8 plays a role in APOPTOSIS by cleaving and activating EFFECTOR CASPASES. Activation of this enzyme can occur via the interaction of its N-terminal death effector domain with DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS.


This graph shows the total number of publications written about "Caspase 8" by people in Harvard Catalyst Profiles by year, and whether "Caspase 8" was a major or minor topic of these publication.
Bar chart showing 152 publications over 22 distinct years, with a maximum of 13 publications in 2004 and 2008
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.