Cardiolipins

"Cardiolipins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Acidic phospholipids composed of two molecules of phosphatidic acid covalently linked to a molecule of glycerol. They occur primarily in mitochondrial inner membranes and in bacterial plasma membranes. They are the main antigenic components of the Wassermann-type antigen that is used in nontreponemal SYPHILIS SERODIAGNOSIS.

Descriptor ID

D002308

MeSH Number(s)

D10.570.755.375.760.400.885.185

D23.050.550.480.330

Concept/Terms

Cardiolipins

Diphosphatidylglycerols

Below are MeSH descriptors whose meaning is more general than "Cardiolipins".

Chemicals and Drugs [D]
Lipids [D10]
Membrane Lipids [D10.570]
Phospholipids [D10.570.755]
Glycerophosphates [D10.570.755.375]
Phosphatidic Acids [D10.570.755.375.760]
Glycerophospholipids [D10.570.755.375.760.400]
Phosphatidylglycerols [D10.570.755.375.760.400.885]
Cardiolipins [D10.570.755.375.760.400.885.185]
Biological Factors [D23]
Antigens [D23.050]
Epitopes [D23.050.550]
Haptens [D23.050.550.480]
Cardiolipins [D23.050.550.480.330]

Below are MeSH descriptors whose meaning is related to "Cardiolipins".

Below are MeSH descriptors whose meaning is more specific than "Cardiolipins".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Cardiolipins" by people in Harvard Catalyst Profiles by year, and whether "Cardiolipins" was a major or minor topic of these publication.

Bar chart showing 34 publications over 20 distinct years, with a maximum of 5 publications in 2023

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	1	1	2
1997	1	0	1
1998	0	1	1
2000	0	1	1
2003	0	1	1
2005	1	0	1
2007	0	1	1
2009	0	1	1
2010	0	3	3
2011	1	2	3
2013	0	3	3
2015	0	1	1
2016	0	1	1
2017	0	1	1
2018	1	0	1
2019	1	1	2
2020	0	2	2
2021	0	2	2
2022	0	1	1
2023	1	4	5

Below are the most recent publications written about "Cardiolipins" by people in Profiles.

Gasdermin D permeabilization of mitochondrial inner and outer membranes accelerates and enhances pyroptosis. Immunity. 2023 Nov 14; 56(11):2523-2541.e8.

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A Cardiolipin from Muribaculum intestinale Induces Antigen-Specific Cytokine Responses. J Am Chem Soc. 2023 11 01; 145(43):23422-23426.

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Revisiting Coley's Toxins: Immunogenic Cardiolipins from Streptococcus pyogenes. J Am Chem Soc. 2023 10 04; 145(39):21183-21188.

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Phospholipids can regulate complex I assembly independent of their role in maintaining mitochondrial membrane integrity. Cell Rep. 2023 08 29; 42(8):112846.

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Genetic modifiers modulate phenotypic expression of tafazzin deficiency in a mouse model of Barth syndrome. Hum Mol Genet. 2023 06 05; 32(12):2055-2067.

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A new murine model of Barth syndrome neutropenia links TAFAZZIN deficiency to increased ER stress-induced apoptosis. Blood Adv. 2022 04 26; 6(8):2557-2577.

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Current and future treatment approaches for Barth syndrome. J Inherit Metab Dis. 2022 01; 45(1):17-28.

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Experimental models of Barth syndrome. J Inherit Metab Dis. 2022 01; 45(1):72-81.

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Cardiolipin deficiency in Barth syndrome is not associated with increased superoxide/H2 O2 production in heart and skeletal muscle mitochondria. FEBS Lett. 2021 02; 595(3):415-432.

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An essential role for cardiolipin in the stability and function of the mitochondrial calcium uniporter. Proc Natl Acad Sci U S A. 2020 07 14; 117(28):16383-16390.

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