Calcium-Calmodulin-Dependent Protein Kinase Kinase
"Calcium-Calmodulin-Dependent Protein Kinase Kinase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A regulatory calcium-calmodulin-dependent protein kinase that specifically phosphorylates CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 1; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 4; and PROTEIN KINASE B. It is a monomeric enzyme that is encoded by at least two different genes.
MeSH Number(s)
D08.811.913.696.620.682.700.125.049
D12.644.360.100.049
D12.776.476.100.049
Concept/Terms
Calcium-Calmodulin-Dependent Protein Kinase Kinase- Calcium-Calmodulin-Dependent Protein Kinase Kinase
- Calcium Calmodulin Dependent Protein Kinase Kinase
- CaMKK
- CaM Kinase I Activator
- CaM-KK
- Calcium-Calmodulin-Dependent Kinase Kinase
- Calcium Calmodulin Dependent Kinase Kinase
- Calcium-Calmodulin-Dependent Protein Kinase I Activator
- Calcium Calmodulin Dependent Protein Kinase I Activator
Calcium-Calmodulin-Dependent Protein Kinase Kinase 2- Calcium-Calmodulin-Dependent Protein Kinase Kinase 2
- Calcium Calmodulin Dependent Protein Kinase Kinase 2
- CaMKKbeta
- CamKK-beta
- Calcium-Calmodulin-Dependent Protein Kinase Kinase beta
- Calcium Calmodulin Dependent Protein Kinase Kinase beta
- CaM-Kinase Kinase beta
- CaM Kinase Kinase beta
Calcium-Calmodulin-Dependent Protein Kinase Kinase 1- Calcium-Calmodulin-Dependent Protein Kinase Kinase 1
- Calcium Calmodulin Dependent Protein Kinase Kinase 1
- CaMKKalpha
- CaM-Kinase Kinase alpha
- CaM Kinase Kinase alpha
- Calcium-Calmodulin-Dependent Protein Kinase Kinase alpha
- Calcium Calmodulin Dependent Protein Kinase Kinase alpha
- CamKK-alpha
- CamKK alpha
Below are MeSH descriptors whose meaning is more general than "Calcium-Calmodulin-Dependent Protein Kinase Kinase".
Below are MeSH descriptors whose meaning is more specific than "Calcium-Calmodulin-Dependent Protein Kinase Kinase".
This graph shows the total number of publications written about "Calcium-Calmodulin-Dependent Protein Kinase Kinase" by people in Harvard Catalyst Profiles by year, and whether "Calcium-Calmodulin-Dependent Protein Kinase Kinase" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 2 | 2 |
| 2003 | 0 | 2 | 2 |
| 2004 | 0 | 4 | 4 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 1 | 2 |
| 2008 | 1 | 2 | 3 |
| 2009 | 1 | 3 | 4 |
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 1 | 2 |
| 2012 | 2 | 1 | 3 |
| 2014 | 1 | 1 | 2 |
| 2018 | 2 | 0 | 2 |
| 2020 | 1 | 0 | 1 |
Below are the most recent publications written about "Calcium-Calmodulin-Dependent Protein Kinase Kinase" by people in Profiles.
-
A prebiotic fructo-oligosaccharide promotes tight junction assembly in intestinal epithelial cells via an AMPK-dependent pathway. Biomed Pharmacother. 2020 Sep; 129:110415.
-
Development and Characterization of Novel Molecular Probes for Ca2+/Calmodulin-Dependent Protein Kinase Kinase, Derived from STO-609. Biochemistry. 2020 05 05; 59(17):1701-1710.
-
Assembly of Peripheral Actomyosin Bundles in Epithelial Cells Is Dependent on the CaMKK2/AMPK Pathway. Cell Rep. 2020 03 24; 30(12):4266-4280.e4.
-
An agonist of a zinc-sensing receptor GPR39 enhances tight junction assembly in intestinal epithelial cells via an AMPK-dependent mechanism. Eur J Pharmacol. 2019 Jan 05; 842:306-313.
-
CaMKK2 kinase domain interacts with the autoinhibitory region through the N-terminal lobe including the RP insert. Biochim Biophys Acta Gen Subj. 2018 10; 1862(10):2304-2313.
-
14-3-3 protein directly interacts with the kinase domain of calcium/calmodulin-dependent protein kinase kinase (CaMKK2). Biochim Biophys Acta Gen Subj. 2018 Jul; 1862(7):1612-1625.
-
Glutamate Dehydrogenase to the Rescue. Mol Cell. 2018 01 04; 69(1):1-2.
-
Flufenamic acid protects against intestinal fluid secretion and barrier leakage in a mouse model of Vibrio cholerae infection through NF-?B inhibition and AMPK activation. Eur J Pharmacol. 2017 Mar 05; 798:94-104.
-
Calcium calmodulin dependent kinase kinase 2 - a novel therapeutic target for gastric adenocarcinoma. Cancer Biol Ther. 2015; 16(2):336-45.
-
Leptin-induced spine formation requires TrpC channels and the CaM kinase cascade in the hippocampus. J Neurosci. 2014 Jul 23; 34(30):10022-33.