"Bufanolides" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cyclopentanophenanthrenes with a 6-membered lactone ring attached at the 17-position and SUGARS attached at the 3-position. They are found in BUFONIDAE and often possess cardiotonic properties.
Below are MeSH descriptors whose meaning is more general than "Bufanolides".
Below are MeSH descriptors whose meaning is more specific than "Bufanolides".
This graph shows the total number of publications written about "Bufanolides" by people in Harvard Catalyst Profiles by year, and whether "Bufanolides" was a major or minor topic of these publication.
To see the data from this visualization as text, click here.
|Year||Major Topic||Minor Topic||Total|
Below are the most recent publications written about "Bufanolides" by people in Profiles.
The spinal microglial IL-10/ß-endorphin pathway accounts for cinobufagin-induced mechanical antiallodynia in bone cancer pain following activation of a7-nicotinic acetylcholine receptors. J Neuroinflammation. 2020 Feb 29; 17(1):75.
Natural Compound Library Screening Identifies New Molecules for the Treatment of Cardiac Fibrosis and Diastolic Dysfunction. Circulation. 2020 03 03; 141(9):751-767.
Telocinobufagin and Marinobufagin Produce Different Effects in LLC-PK1 Cells: A Case of Functional Selectivity of Bufadienolides. Int J Mol Sci. 2018 Sep 14; 19(9).
Bufalin induces apoptosis in vitro and has Antitumor activity against human lung cancer xenografts in vivo. Environ Toxicol. 2017 Apr; 32(4):1305-1317.
Bufalin derivative BF211 inhibits proteasome activity in human lung cancer cells in vitro by inhibiting ß1 subunit expression and disrupting proteasome assembly. Acta Pharmacol Sin. 2016 Jul; 37(7):908-18.
Cardenolides and bufadienolides as hormones: what is missing? Am J Physiol Renal Physiol. 2012 Apr 15; 302(8):F957-8.
Endogenous ouabain regulates cell viability. Am J Physiol Cell Physiol. 2012 Jan 15; 302(2):C442-52.
Spironolactone attenuates experimental uremic cardiomyopathy by antagonizing marinobufagenin. Hypertension. 2009 Dec; 54(6):1313-20.
Marinobufagenin induces increases in procollagen expression in a process involving protein kinase C and Fli-1: implications for uremic cardiomyopathy. Am J Physiol Renal Physiol. 2009 May; 296(5):F1219-26.
The cardiotonic steroid hormone marinobufagenin induces renal fibrosis: implication of epithelial-to-mesenchymal transition. Am J Physiol Renal Physiol. 2009 Apr; 296(4):F922-34.