"Brugia malayi" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A species of parasitic nematode causing Malayan filariasis and having a distribution centering roughly on the Malay peninsula. The life cycle of B. malayi is similar to that of WUCHERERIA BANCROFTI, except that in most areas the principal mosquito vectors belong to the genus Mansonia.
MeSH Number(s)
B01.050.500.500.294.700.750.700.300.088.500
Concept/Terms
Brugia malayi- Brugia malayi
- Brugia malayus
- malayi, Brugia
- malayus, Brugia
Below are MeSH descriptors whose meaning is more general than "Brugia malayi".
Below are MeSH descriptors whose meaning is more specific than "Brugia malayi".
This graph shows the total number of publications written about "Brugia malayi" by people in Harvard Catalyst Profiles by year, and whether "Brugia malayi" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 1997 | 2 | 0 | 2 |
| 1998 | 0 | 1 | 1 |
Below are the most recent publications written about "Brugia malayi" by people in Profiles.
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Crystal structure of Brugia malayi venom allergen-like protein-1 (BmVAL-1), a vaccine candidate for lymphatic filariasis. Int J Parasitol. 2018 04; 48(5):371-378.
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Cofactor-independent phosphoglycerate mutase from nematodes has limited druggability, as revealed by two high-throughput screens. PLoS Negl Trop Dis. 2014; 8(1):e2628.
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Therapeutic efficacy of poly (lactic-co-glycolic acid) nanoparticles encapsulated ivermectin (nano-ivermectin) against brugian filariasis in experimental rodent model. Parasitol Res. 2014 Feb; 113(2):681-91.
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Genomics of Loa loa, a Wolbachia-free filarial parasite of humans. Nat Genet. 2013 May; 45(5):495-500.
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Ivermectin disrupts the function of the excretory-secretory apparatus in microfilariae of Brugia malayi. Proc Natl Acad Sci U S A. 2010 Nov 16; 107(46):20120-5.
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The heme biosynthetic pathway of the obligate Wolbachia endosymbiont of Brugia malayi as a potential anti-filarial drug target. PLoS Negl Trop Dis. 2009 Jul 14; 3(7):e475.
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The Wolbachia endosymbiont of Brugia malayi has an active phosphoglycerate mutase: a candidate target for anti-filarial therapies. Parasitol Res. 2009 Apr; 104(5):1047-52.
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The Wolbachia endosymbiont of Brugia malayi has an active pyruvate phosphate dikinase. Mol Biochem Parasitol. 2008 Aug; 160(2):163-6.
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Molecular and biochemical characterization of nematode cofactor independent phosphoglycerate mutases. Mol Biochem Parasitol. 2007 Dec; 156(2):210-6.
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Preexposure to live Brugia malayi microfilariae alters the innate response of human dendritic cells to Mycobacterium tuberculosis. J Infect Dis. 2006 Jan 15; 193(2):196-204.