"Bone Marrow Purging" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Techniques for the removal of subpopulations of cells (usually residual tumor cells) from the bone marrow ex vivo before it is infused. The purging is achieved by a variety of agents including pharmacologic agents, biophysical agents (laser photoirradiation or radioisotopes) and immunologic agents. Bone marrow purging is used in both autologous and allogeneic BONE MARROW TRANSPLANTATION.
Below are MeSH descriptors whose meaning is more general than "Bone Marrow Purging".
Below are MeSH descriptors whose meaning is more specific than "Bone Marrow Purging".
This graph shows the total number of publications written about "Bone Marrow Purging" by people in Harvard Catalyst Profiles by year, and whether "Bone Marrow Purging" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 2 | 3 | 5 |
| 1995 | 3 | 2 | 5 |
| 1996 | 1 | 5 | 6 |
| 1997 | 1 | 2 | 3 |
| 1998 | 1 | 2 | 3 |
| 1999 | 0 | 1 | 1 |
| 2000 | 2 | 0 | 2 |
| 2001 | 2 | 0 | 2 |
| 2002 | 0 | 3 | 3 |
| 2003 | 1 | 1 | 2 |
| 2004 | 2 | 1 | 3 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
Below are the most recent publications written about "Bone Marrow Purging" by people in Profiles.
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Transplant tolerance: bench to bedside--26th annual Samuel Jason Mixter Lecture. Arch Surg. 2011 May; 146(5):501-5.
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Cardiovascular changes after PMMA vertebroplasty in sheep: the effect of bone marrow removal using pulsed jet-lavage. Eur Spine J. 2010 Nov; 19(11):1913-20.
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Outcome of high-risk stage 3 neuroblastoma with myeloablative therapy and 13-cis-retinoic acid: a report from the Children's Oncology Group. Pediatr Blood Cancer. 2009 Jan; 52(1):44-50.
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Flow electroporation with pulsed electric fields for purging tumor cells. Methods Mol Biol. 2008; 423:301-10.
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Successful treatment of primary plasma cell leukaemia by allogeneic stem cell transplantation from haploidentical sibling. Jpn J Clin Oncol. 2007 Dec; 37(12):969-72.
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Long-term survival after autologous bone marrow transplantation for follicular lymphoma in first remission. Biol Blood Marrow Transplant. 2007 Sep; 13(9):1057-65.
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T-cell-depleted CD34+ cell transplantation from an HLA-mismatched donor in a low-birthweight infant with X-linked severe combined immunodeficiency. J Pediatr Hematol Oncol. 2005 Feb; 27(2):80-4.
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B-cell purging in autologous stem-cell transplantation for non-Hodgkin lymphoma. Lancet Oncol. 2004 Dec; 5(12):711-7.
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Flowing cells through pulsed electric fields efficiently purges stem cell preparations of contaminating myeloma cells while preserving stem cell function. Blood. 2005 Mar 01; 105(5):2235-8.
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An update on the role of high-dose therapy with autologous or allogeneic stem cell transplantation in mantle cell lymphoma. Curr Opin Oncol. 2004 Mar; 16(2):106-13.