"Azaserine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Antibiotic substance produced by various Streptomyces species. It is an inhibitor of enzymatic activities that involve glutamine and is used as an antineoplastic and immunosuppressive agent.
Concept/Terms
Azaserine- Azaserine
- Azeserine
- O-Diazoacetyl-L-serine
- O Diazoacetyl L serine
Below are MeSH descriptors whose meaning is more general than "Azaserine".
Below are MeSH descriptors whose meaning is more specific than "Azaserine".
This graph shows the total number of publications written about "Azaserine" by people in Harvard Catalyst Profiles by year, and whether "Azaserine" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
Below are the most recent publications written about "Azaserine" by people in Profiles.
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Small-Molecule Screen Identifies De Novo Nucleotide Synthesis as a Vulnerability of Cells Lacking SIRT3. Cell Rep. 2018 02 20; 22(8):1945-1955.
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Identification and characterization of genes related to the production of organic acids in yeast. J Biosci Bioeng. 2012 May; 113(5):556-61.
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Reactive oxygen species blockade and action of insulin on expression of angiotensinogen gene in proximal tubular cells. J Endocrinol. 2004 Dec; 183(3):535-50.
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High glucose stimulates angiotensinogen gene expression and cell hypertrophy via activation of the hexosamine biosynthesis pathway in rat kidney proximal tubular cells. Endocrinology. 2003 Oct; 144(10):4338-49.
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On the mechanism of action of antibiotics which act as irreversible enzyme inhibitors. Biochem Pharmacol. 1975 Jun 15; 24(11-12):1153-60.
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Human renal allografts. Analysis of lesions in long-term survivors. Hum Pathol. 1971 Jun; 2(2):253-98.
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Asparagine biosynthesis in human KB tumor cells: inhibitor studies with asparagine and glutamine antagonists. Cancer Res. 1970 Apr; 30(4):1081-3.
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Five years' experience in renal transplantation with immunosuppressive drugs: survival, function, complications, and the role of lymphocyte depletion by thoracic duct fistula. Ann Surg. 1968 Sep; 168(3):416-35.
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The prevention of fatty liver by administration of adenosine triphosphate. Lab Invest. 1967 Apr; 16(4):604-15.
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A study of the effects of intra-arterial immunosuppressive drug therapy on canine renal allografts. Surgery. 1966 Dec; 60(6):1242-50.