"Autophagy" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The segregation and degradation of damaged or unwanted cytoplasmic constituents by autophagic vacuoles (cytolysosomes) composed of LYSOSOMES containing cellular components in the process of digestion; it plays an important role in BIOLOGICAL METAMORPHOSIS of amphibians, in the removal of bone by osteoclasts, and in the degradation of normal cell components in nutritional deficiency states.
MeSH Number(s)
G04.299.139.399
G04.299.482.350.091
Concept/Terms
Autophagy- Autophagy
- Autophagies
- Autophagocytosis
- Autophagy, Cellular
- Autophagies, Cellular
- Cellular Autophagies
- Cellular Autophagy
Programmed Cell Death, Type II- Programmed Cell Death, Type II
- Autophagic Programmed Cell Death
- Autophagic Cell Death
- Autophagic Cell Deaths
- Cell Death, Autophagic
- Cell Deaths, Autophagic
- Death, Autophagic Cell
- Deaths, Autophagic Cell
Below are MeSH descriptors whose meaning is more general than "Autophagy".
Below are MeSH descriptors whose meaning is more specific than "Autophagy".
This graph shows the total number of publications written about "Autophagy" by people in Harvard Catalyst Profiles by year, and whether "Autophagy" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1998 | 1 | 0 | 1 |
| 1999 | 1 | 0 | 1 |
| 2000 | 1 | 0 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 1 | 1 | 2 |
| 2004 | 2 | 0 | 2 |
| 2005 | 3 | 0 | 3 |
| 2006 | 2 | 1 | 3 |
| 2007 | 8 | 4 | 12 |
| 2008 | 15 | 9 | 24 |
| 2009 | 19 | 11 | 30 |
| 2010 | 24 | 14 | 38 |
| 2011 | 27 | 19 | 46 |
| 2012 | 30 | 21 | 51 |
| 2013 | 51 | 16 | 67 |
| 2014 | 41 | 26 | 67 |
| 2015 | 42 | 22 | 64 |
| 2016 | 45 | 39 | 84 |
| 2017 | 42 | 31 | 73 |
| 2018 | 33 | 29 | 62 |
| 2019 | 40 | 29 | 69 |
| 2020 | 30 | 29 | 59 |
| 2021 | 17 | 31 | 48 |
| 2022 | 8 | 33 | 41 |
| 2023 | 0 | 2 | 2 |
Below are the most recent publications written about "Autophagy" by people in Profiles.
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AMPK-driven Macrophage Responses Are Autophagy Dependent in Experimental Bronchopulmonary Dysplasia. Am J Respir Cell Mol Biol. 2023 03; 68(3):279-287.
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Autophagy as a Therapeutic Target for Chronic Kidney Disease and the Roles of TGF-ß1 in Autophagy and Kidney Fibrosis. Cells. 2023 01 26; 12(3).
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Palmitoylation prevents sustained inflammation by limiting NLRP3 inflammasome activation through chaperone-mediated autophagy. Mol Cell. 2023 Jan 19; 83(2):281-297.e10.
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A key virulence effector from cyst nematodes targets host autophagy to promote nematode parasitism. New Phytol. 2023 02; 237(4):1374-1390.
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Mitochondrial redox impairment and enhanced autophagy in peripheral blood mononuclear cells from type 1 diabetic patients. Redox Biol. 2022 12; 58:102551.
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Metformin alleviates bone loss in ovariectomized mice through inhibition of autophagy of osteoclast precursors mediated by E2F1. Cell Commun Signal. 2022 10 25; 20(1):165.
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Selective autophagy of RIPosomes maintains innate immune homeostasis during bacterial infection. EMBO J. 2022 12 01; 41(23):e111289.
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IL-33 mediates Pseudomonas induced airway fibrogenesis and is associated with CLAD. J Heart Lung Transplant. 2023 Jan; 42(1):53-63.
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NCOA4-Mediated Ferritinophagy Is a Pancreatic Cancer Dependency via Maintenance of Iron Bioavailability for Iron-Sulfur Cluster Proteins. Cancer Discov. 2022 09 02; 12(9):2180-2197.
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Loss of endosomal exchanger NHE6 leads to pathological changes in tau in human neurons. Stem Cell Reports. 2022 09 13; 17(9):2111-2126.