Harvard Catalyst Profiles

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Alu Elements

"Alu Elements" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

The Alu sequence family (named for the restriction endonuclease cleavage enzyme Alu I) is the most highly repeated interspersed repeat element in humans (over a million copies). It is derived from the 7SL RNA component of the SIGNAL RECOGNITION PARTICLE and contains an RNA polymerase III promoter. Transposition of this element into coding and regulatory regions of genes is responsible for many heritable diseases.


This graph shows the total number of publications written about "Alu Elements" by people in Harvard Catalyst Profiles by year, and whether "Alu Elements" was a major or minor topic of these publication.
Bar chart showing 46 publications over 19 distinct years, with a maximum of 6 publications in 2011
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.