Aequorin

"Aequorin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A photoprotein isolated from the bioluminescent jellyfish Aequorea. It emits visible light by an intramolecular reaction when a trace amount of calcium ion is added. The light-emitting moiety in the bioluminescence reaction is believed to be 2-amino-3-benzyl-5-(p-hydroxyphenyl)pyrazine (AF-350).

Descriptor ID

D000331

MeSH Number(s)

D12.776.532.020

Concept/Terms

Aequorin

Below are MeSH descriptors whose meaning is more general than "Aequorin".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Luminescent Proteins [D12.776.532]
Aequorin [D12.776.532.020]

Below are MeSH descriptors whose meaning is related to "Aequorin".

Below are MeSH descriptors whose meaning is more specific than "Aequorin".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Aequorin" by people in Harvard Catalyst Profiles by year, and whether "Aequorin" was a major or minor topic of these publication.

Bar chart showing 9 publications over 8 distinct years, with a maximum of 2 publications in 1996

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	1	1	2
1999	0	1	1
2000	1	0	1
2001	0	1	1
2005	0	1	1
2008	0	1	1
2012	1	0	1
2016	1	0	1

Below are the most recent publications written about "Aequorin" by people in Profiles.

Filling a GAP-An Optimized Probe for ER Ca(2+) Imaging In Vivo. Cell Chem Biol. 2016 06 23; 23(6):641-3.

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p53 at the endoplasmic reticulum regulates apoptosis in a Ca2+-dependent manner. Proc Natl Acad Sci U S A. 2015 Feb 10; 112(6):1779-84.

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A high-throughput assay for connexin 43 (Cx43, GJA1) gap junctions using codon-optimized aequorin. Assay Drug Dev Technol. 2013 Mar; 11(2):93-100.

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Noninvasive monitoring of neural activity with bioluminescence. Neurosurgery. 2010 Jun; 66(6):N16-7.

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Mutations in prokineticin 2 and prokineticin receptor 2 genes in human gonadotrophin-releasing hormone deficiency: molecular genetics and clinical spectrum. J Clin Endocrinol Metab. 2008 Sep; 93(9):3551-9.

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Aequorin-based homogeneous cortisol immunoassay for analysis of saliva samples. Bioconjug Chem. 2007 Nov-Dec; 18(6):1772-7.

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Endoplasmic reticulum stress and alteration in calcium homeostasis are involved in cadmium-induced apoptosis. Cell Calcium. 2008 Feb; 43(2):184-95.

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Aequorin chimeras as valuable tool in the measurement of Ca2+ concentration during cadmium injury. Toxicology. 2005 Mar 30; 208(3):389-98.

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Measurement of free [Ca²+] changes in agonist-sensitive internal stores using compartmentalized fluorescent indicators. Methods Mol Biol. 2005; 312:229-47.

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Functional characterization of mouse alpha4beta2 nicotinic acetylcholine receptors stably expressed in HEK293T cells. J Neurochem. 2004 Dec; 91(5):1138-50.

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