"Adjuvants, Immunologic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Substances that augment, stimulate, activate, potentiate, or modulate the immune response at either the cellular or humoral level. The classical agents (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contain bacterial antigens. Some are endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Their mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy of many biological response modifiers is related to their antigen-specific immunoadjuvanticity.
Concept/Terms
Adjuvants, Immunologic- Adjuvants, Immunologic
- Adjuvants, Immunological
- Immunological Adjuvants
- Immunological Adjuvant
- Adjuvant, Immunological
- Adjuvant, Immunologic
- Immunologic Adjuvant
- Immunopotentiators
- Immunoactivators
- Immunoadjuvants
- Immunostimulants
- Immunologic Adjuvants
Below are MeSH descriptors whose meaning is more general than "Adjuvants, Immunologic".
Below are MeSH descriptors whose meaning is more specific than "Adjuvants, Immunologic".
This graph shows the total number of publications written about "Adjuvants, Immunologic" by people in Harvard Catalyst Profiles by year, and whether "Adjuvants, Immunologic" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 0 | 5 | 5 |
| 1994 | 5 | 1 | 6 |
| 1995 | 3 | 6 | 9 |
| 1996 | 6 | 1 | 7 |
| 1997 | 9 | 5 | 14 |
| 1998 | 7 | 5 | 12 |
| 1999 | 9 | 9 | 18 |
| 2000 | 9 | 8 | 17 |
| 2001 | 9 | 14 | 23 |
| 2002 | 19 | 10 | 29 |
| 2003 | 22 | 16 | 38 |
| 2004 | 17 | 6 | 23 |
| 2005 | 12 | 11 | 23 |
| 2006 | 15 | 8 | 23 |
| 2007 | 11 | 6 | 17 |
| 2008 | 8 | 13 | 21 |
| 2009 | 4 | 12 | 16 |
| 2010 | 7 | 6 | 13 |
| 2011 | 9 | 8 | 17 |
| 2012 | 11 | 14 | 25 |
| 2013 | 8 | 11 | 19 |
| 2014 | 8 | 11 | 19 |
| 2015 | 17 | 8 | 25 |
| 2016 | 11 | 11 | 22 |
| 2017 | 8 | 10 | 18 |
| 2018 | 9 | 8 | 17 |
| 2019 | 8 | 18 | 26 |
| 2020 | 12 | 13 | 25 |
| 2021 | 11 | 14 | 25 |
| 2022 | 2 | 35 | 37 |
| 2023 | 1 | 20 | 21 |
Below are the most recent publications written about "Adjuvants, Immunologic" by people in Profiles.
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In Situ Cocktail Nanovaccine for Cancer Immunotherapy. Adv Sci (Weinh). 2023 11; 10(31):e2207697.
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Immunogenicity and Safety of Hepatitis B Virus (HBV) Vaccine With a Toll-Like Receptor 9 Agonist Adjuvant in HBV Vaccine-Naïve People With Human Immunodeficiency Virus. Clin Infect Dis. 2023 08 14; 77(3):414-418.
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Adjuvant everolimus after surgery for renal cell carcinoma (EVEREST): a double-blind, placebo-controlled, randomised, phase 3 trial. Lancet. 2023 09 23; 402(10407):1043-1051.
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ARTISTRY-7: phase III trial of nemvaleukin alfa plus pembrolizumab vs chemotherapy for platinum-resistant ovarian cancer. Future Oncol. 2023 Jul; 19(23):1577-1591.
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Intravenous heterologous prime-boost vaccination activates innate and adaptive immunity to promote tumor regression. Cell Rep. 2023 06 27; 42(6):112599.
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The case for adjuvant BRAF-targeted therapy versus adjuvant anti-PD-1 therapy for patients with resected, high-risk melanoma. Cancer. 2023 07 15; 129(14):2117-2121.
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Novel Adjuvant S-540956 Targets Lymph Nodes and Reduces Genital Recurrences and Vaginal Shedding of HSV-2 DNA When Administered with HSV-2 Glycoprotein D as a Therapeutic Vaccine in Guinea Pigs. Viruses. 2023 05 10; 15(5).
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Association of BCG Vaccine Treatment With Death and Dementia in Patients With Non-Muscle-Invasive Bladder Cancer. JAMA Netw Open. 2023 05 01; 6(5):e2314336.
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Engineering kinetics of TLR7/8 agonist release from bottlebrush prodrugs enables tumor-focused immune stimulation. Sci Adv. 2023 04 21; 9(16):eadg2239.
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Safety of COVID-19 vaccines during pregnancy: A systematic review and meta-analysis. Vaccine. 2023 06 07; 41(25):3688-3700.