Harvard Catalyst Profiles

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Adenomatous Polyposis Coli

"Adenomatous Polyposis Coli" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

A polyposis syndrome due to an autosomal dominant mutation of the APC genes (GENES, APC) on CHROMOSOME 5. The syndrome is characterized by the development of hundreds of ADENOMATOUS POLYPS in the COLON and RECTUM of affected individuals by early adulthood. The lifetime risk of colorectal cancer in these patients reaches 100 percent by age 60.


This graph shows the total number of publications written about "Adenomatous Polyposis Coli" by people in Harvard Catalyst Profiles by year, and whether "Adenomatous Polyposis Coli" was a major or minor topic of these publication.
Bar chart showing 134 publications over 28 distinct years, with a maximum of 10 publications in 1999
To see the data from this visualization as text, click here.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.