Adaptor Proteins, Signal Transducing
"Adaptor Proteins, Signal Transducing" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A broad category of carrier proteins that play a role in SIGNAL TRANSDUCTION. They generally contain several modular domains, each of which having its own binding activity, and act by forming complexes with other intracellular-signaling molecules. Signal-transducing adaptor proteins lack enzyme activity, however their activity can be modulated by other signal-transducing enzymes
MeSH Number(s)
D12.644.360.024
D12.776.157.057
D12.776.476.024
Below are MeSH descriptors whose meaning is more general than "Adaptor Proteins, Signal Transducing".
Below are MeSH descriptors whose meaning is more specific than "Adaptor Proteins, Signal Transducing".
This graph shows the total number of publications written about "Adaptor Proteins, Signal Transducing" by people in Harvard Catalyst Profiles by year, and whether "Adaptor Proteins, Signal Transducing" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1992 | 1 | 0 | 1 |
| 1993 | 2 | 2 | 4 |
| 1994 | 7 | 6 | 13 |
| 1995 | 20 | 3 | 23 |
| 1996 | 19 | 6 | 25 |
| 1997 | 17 | 8 | 25 |
| 1998 | 11 | 17 | 28 |
| 1999 | 14 | 23 | 37 |
| 2000 | 21 | 23 | 44 |
| 2001 | 19 | 35 | 54 |
| 2002 | 13 | 34 | 47 |
| 2003 | 15 | 32 | 47 |
| 2004 | 16 | 48 | 64 |
| 2005 | 14 | 40 | 54 |
| 2006 | 36 | 51 | 87 |
| 2007 | 24 | 38 | 62 |
| 2008 | 38 | 49 | 87 |
| 2009 | 32 | 41 | 73 |
| 2010 | 41 | 53 | 94 |
| 2011 | 44 | 40 | 84 |
| 2012 | 42 | 68 | 110 |
| 2013 | 45 | 54 | 99 |
| 2014 | 52 | 53 | 105 |
| 2015 | 50 | 62 | 112 |
| 2016 | 46 | 51 | 97 |
| 2017 | 48 | 46 | 94 |
| 2018 | 35 | 29 | 64 |
| 2019 | 43 | 24 | 67 |
| 2020 | 32 | 39 | 71 |
| 2021 | 33 | 28 | 61 |
| 2022 | 0 | 6 | 6 |
Below are the most recent publications written about "Adaptor Proteins, Signal Transducing" by people in Profiles.
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Autoantibodies Against Proteins Previously Associated With Autoimmunity in Adult and Pediatric Patients With COVID-19 and Children With MIS-C. Front Immunol. 2022; 13:841126.
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The neuronal-specific isoform of BIN1 regulates ß-secretase cleavage of APP and Aß generation in a RIN3-dependent manner. Sci Rep. 2022 Mar 03; 12(1):3486.
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Functional dissection of inherited non-coding variation influencing multiple myeloma risk. Nat Commun. 2022 01 10; 13(1):151.
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Genetic Determinants of Sudden Unexpected Death in Pediatrics. Genet Med. 2022 Apr; 24(4):839-850.
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YAP1 and PRDM14 converge to promote cell survival and tumorigenesis. Dev Cell. 2022 01 24; 57(2):212-227.e8.
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DNA-PK promotes activation of the survival kinase AKT in response to DNA damage through an mTORC2-ECT2 pathway. Sci Signal. 2022 01 04; 15(715):eabh2290.
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TRACE generates fluorescent human reporter cell lines to characterize epigenetic pathways. Mol Cell. 2022 01 20; 82(2):479-491.e7.
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Notch1 and Notch3 coordinate for pericyte-induced stabilization of vasculature. Am J Physiol Cell Physiol. 2022 02 01; 322(2):C185-C196.
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Oxidized Phospholipids Promote NETosis and Arterial Thrombosis in LNK(SH2B3) Deficiency. Circulation. 2021 12 14; 144(24):1940-1954.
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A ubiquitous disordered protein interaction module orchestrates transcription elongation. Science. 2021 Nov 26; 374(6571):1113-1121.