Adaptor Proteins, Signal Transducing
"Adaptor Proteins, Signal Transducing" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A broad category of carrier proteins that play a role in SIGNAL TRANSDUCTION. They generally contain several modular domains, each of which having its own binding activity, and act by forming complexes with other intracellular-signaling molecules. Signal-transducing adaptor proteins lack enzyme activity, however their activity can be modulated by other signal-transducing enzymes
MeSH Number(s)
D12.644.360.024
D12.776.157.057
D12.776.476.024
Below are MeSH descriptors whose meaning is more general than "Adaptor Proteins, Signal Transducing".
Below are MeSH descriptors whose meaning is more specific than "Adaptor Proteins, Signal Transducing".
This graph shows the total number of publications written about "Adaptor Proteins, Signal Transducing" by people in Harvard Catalyst Profiles by year, and whether "Adaptor Proteins, Signal Transducing" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 2 | 2 | 4 |
| 1994 | 7 | 6 | 13 |
| 1995 | 20 | 2 | 22 |
| 1996 | 19 | 6 | 25 |
| 1997 | 17 | 8 | 25 |
| 1998 | 10 | 15 | 25 |
| 1999 | 14 | 21 | 35 |
| 2000 | 21 | 23 | 44 |
| 2001 | 19 | 34 | 53 |
| 2002 | 14 | 32 | 46 |
| 2003 | 13 | 30 | 43 |
| 2004 | 14 | 48 | 62 |
| 2005 | 13 | 39 | 52 |
| 2006 | 36 | 49 | 85 |
| 2007 | 24 | 39 | 63 |
| 2008 | 36 | 47 | 83 |
| 2009 | 30 | 40 | 70 |
| 2010 | 39 | 51 | 90 |
| 2011 | 41 | 38 | 79 |
| 2012 | 41 | 61 | 102 |
| 2013 | 44 | 50 | 94 |
| 2014 | 51 | 54 | 105 |
| 2015 | 51 | 62 | 113 |
| 2016 | 45 | 46 | 91 |
| 2017 | 48 | 46 | 94 |
| 2018 | 32 | 33 | 65 |
| 2019 | 46 | 27 | 73 |
| 2020 | 35 | 39 | 74 |
| 2021 | 38 | 31 | 69 |
| 2022 | 4 | 23 | 27 |
| 2023 | 0 | 2 | 2 |
Below are the most recent publications written about "Adaptor Proteins, Signal Transducing" by people in Profiles.
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Pleiotropic role of TRAF7 in skull-base meningiomas and congenital heart disease. Proc Natl Acad Sci U S A. 2023 Apr 18; 120(16):e2214997120.
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Targeting Transcription Factors in Cancer: From "Undruggable" to "Druggable". Methods Mol Biol. 2023; 2594:107-131.
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Insights into the aberrant CDK4/6 signaling pathway as a therapeutic target in tumorigenesis. Adv Protein Chem Struct Biol. 2023; 135:179-201.
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High-throughput morphometric and transcriptomic profiling uncovers composition of naïve and sensory-deprived cortical cholinergic VIP/CHAT neurons. EMBO J. 2023 01 04; 42(1):e110565.
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Sleeping beauty generated CD19 CAR T-Cell therapy for advanced B-Cell hematological malignancies. Front Immunol. 2022; 13:1032397.
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Identification of a minority population of LMO2+ breast cancer cells that integrate into the vasculature and initiate metastasis. Sci Adv. 2022 11 11; 8(45):eabm3548.
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Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis. Nat Genet. 2022 11; 54(11):1640-1651.
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Clinical, immunological, molecular and therapeutic findings in monogenic immune dysregulation diseases: Middle East and North Africa registry. Clin Immunol. 2022 11; 244:109131.
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DPP9 deficiency: An inflammasomopathy that can be rescued by lowering NLRP1/IL-1 signaling. Sci Immunol. 2022 09 16; 7(75):eabi4611.
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Clinically Complex LRBA Deficiency Due to a Founder Allele in the Georgian Jewish Population. J Clin Immunol. 2023 Jan; 43(1):151-164.