Adaptor Proteins, Signal Transducing
"Adaptor Proteins, Signal Transducing" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A broad category of carrier proteins that play a role in SIGNAL TRANSDUCTION. They generally contain several modular domains, each of which having its own binding activity, and act by forming complexes with other intracellular-signaling molecules. Signal-transducing adaptor proteins lack enzyme activity, however their activity can be modulated by other signal-transducing enzymes
MeSH Number(s)
D12.644.360.024
D12.776.157.057
D12.776.476.024
Below are MeSH descriptors whose meaning is more general than "Adaptor Proteins, Signal Transducing".
Below are MeSH descriptors whose meaning is more specific than "Adaptor Proteins, Signal Transducing".
This graph shows the total number of publications written about "Adaptor Proteins, Signal Transducing" by people in Harvard Catalyst Profiles by year, and whether "Adaptor Proteins, Signal Transducing" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1992 | 1 | 0 | 1 |
| 1993 | 1 | 1 | 2 |
| 1994 | 6 | 7 | 13 |
| 1995 | 20 | 3 | 23 |
| 1996 | 18 | 6 | 24 |
| 1997 | 17 | 7 | 24 |
| 1998 | 11 | 16 | 27 |
| 1999 | 14 | 23 | 37 |
| 2000 | 21 | 20 | 41 |
| 2001 | 19 | 31 | 50 |
| 2002 | 15 | 27 | 42 |
| 2003 | 15 | 26 | 41 |
| 2004 | 18 | 44 | 62 |
| 2005 | 13 | 42 | 55 |
| 2006 | 37 | 46 | 83 |
| 2007 | 29 | 33 | 62 |
| 2008 | 39 | 47 | 86 |
| 2009 | 34 | 37 | 71 |
| 2010 | 44 | 39 | 83 |
| 2011 | 47 | 32 | 79 |
| 2012 | 50 | 53 | 103 |
| 2013 | 48 | 39 | 87 |
| 2014 | 55 | 39 | 94 |
| 2015 | 53 | 43 | 96 |
| 2016 | 47 | 31 | 78 |
| 2017 | 51 | 29 | 80 |
| 2018 | 36 | 20 | 56 |
| 2019 | 43 | 25 | 68 |
| 2020 | 18 | 19 | 37 |
| 2021 | 1 | 3 | 4 |
Below are the most recent publications written about "Adaptor Proteins, Signal Transducing" by people in Profiles.
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Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture. Nat Genet. 2021 03; 53(3):294-303.
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Human DDK rescues stalled forks and counteracts checkpoint inhibition at unfired origins to complete DNA replication. Mol Cell. 2021 02 04; 81(3):426-441.e8.
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Factors that mold the nuclear landscape of HIV-1 integration. Nucleic Acids Res. 2021 01 25; 49(2):621-635.
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Mechanism of filament formation in UPA-promoted CARD8 and NLRP1 inflammasomes. Nat Commun. 2021 01 08; 12(1):189.
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Mitochondrial dysfunction induces RNA interference in C. elegans through a pathway homologous to the mammalian RIG-I antiviral response. PLoS Biol. 2020 12; 18(12):e3000996.
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Recurrent YAP1 and MAML2 Gene Rearrangements in Retiform and Composite Hemangioendothelioma. Am J Surg Pathol. 2020 12; 44(12):1677-1684.
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NCKAP1 Disruptive Variants Lead to a Neurodevelopmental Disorder with Core Features of Autism. Am J Hum Genet. 2020 11 05; 107(5):963-976.
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p31comet promotes homologous recombination by inactivating REV7 through the TRIP13 ATPase. Proc Natl Acad Sci U S A. 2020 10 27; 117(43):26795-26803.
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ERBB2 drives YAP activation and EMT-like processes during cardiac regeneration. Nat Cell Biol. 2020 11; 22(11):1346-1356.
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Hedgehog Pathway Activation Requires Coreceptor-Catalyzed, Lipid-Dependent Relay of the Sonic Hedgehog Ligand. Dev Cell. 2020 11 23; 55(4):450-467.e8.