Activins

"Activins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Activins are produced in the pituitary, gonads, and other tissues. By acting locally, they stimulate pituitary FSH secretion and have diverse effects on cell differentiation and embryonic development. Activins are glycoproteins that are hetero- or homodimers of INHIBIN-BETA SUBUNITS.

Descriptor ID

D028341

MeSH Number(s)

D06.472.334.500

D06.472.699.009

D12.644.548.009

D12.776.395.022

Concept/Terms

Activins

Below are MeSH descriptors whose meaning is more general than "Activins".

Chemicals and Drugs [D]
Hormones, Hormone Substitutes, and Hormone Antagonists [D06]
Hormones [D06.472]
Gonadal Hormones [D06.472.334]
Activins [D06.472.334.500]
Peptide Hormones [D06.472.699]
Activins [D06.472.699.009]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Peptide Hormones [D12.644.548]
Activins [D12.644.548.009]
Proteins [D12.776]
Glycoproteins [D12.776.395]
Activins [D12.776.395.022]

Below are MeSH descriptors whose meaning is related to "Activins".

Below are MeSH descriptors whose meaning is more specific than "Activins".

Activins
Inhibin-beta Subunits

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Activins" by people in Harvard Catalyst Profiles by year, and whether "Activins" was a major or minor topic of these publication.

Bar chart showing 131 publications over 30 distinct years, with a maximum of 10 publications in 1996

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	0	1	1
1995	0	3	3
1996	0	10	10
1997	0	2	2
1998	0	4	4
2000	0	8	8
2001	1	5	6
2002	5	3	8
2003	1	2	3
2004	7	2	9
2005	2	1	3
2006	3	0	3
2007	1	2	3
2008	2	0	2
2009	2	1	3
2010	3	1	4
2011	4	3	7
2012	2	3	5
2013	3	0	3
2014	1	0	1
2015	2	2	4
2016	2	1	3
2017	4	1	5
2018	5	2	7
2019	2	4	6
2020	5	2	7
2021	2	2	4
2022	1	3	4
2023	0	2	2
2024	1	0	1

Below are the most recent publications written about "Activins" by people in Profiles.

Roles of Activin A and Gpnmb in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD). Diabetes. 2024 Feb 01; 73(2):260-279.

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Circulating hormones in biopsy-proven steatotic liver disease and steatohepatitis: A Multicenter Observational Study. Metabolism. 2023 11; 148:155694.

View in: PubMed
Single-cell transcriptomics of human cholesteatoma identifies an activin A-producing osteoclastogenic fibroblast subset inducing bone destruction. Nat Commun. 2023 08 03; 14(1):4417.

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Activins, follistatins and inhibins in postmenopausal osteoporosis: A proof of concept, case-control study. Metabolism. 2023 04; 141:155397.

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Beneficial Effects of Moderate Hepatic Activin A Expression on Metabolic Pathways, Inflammation, and Atherosclerosis. Arterioscler Thromb Vasc Biol. 2023 02; 43(2):330-349.

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Embryo Quality May Be Associated With Serum Inhibin B Levels but Not With Serum or Follicular Fluid Levels of Other Components of the Activin-Follistatin-Inhibin Axis. Endocr Pract. 2022 Oct; 28(10):1086-1090.

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Intra-epithelial non-canonical Activin A signaling safeguards prostate progenitor quiescence. EMBO Rep. 2022 05 04; 23(5):e54049.

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The Activin/FLRG Pathway Associates with Poor COVID-19 Outcomes in Hospitalized Patients. Mol Cell Biol. 2022 01 20; 42(1):e0046721.

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Structure of AMH bound to AMHR2 provides insight into a unique signaling pair in the TGF-ß family. Proc Natl Acad Sci U S A. 2021 06 29; 118(26).

View in: PubMed
activin-2 is required for regeneration of polarity on the planarian anterior-posterior axis. PLoS Genet. 2021 03; 17(3):e1009466.

View in: PubMed

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