"Acetylglucosaminidase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A beta-N-Acetylhexosaminidase that catalyzes the hydrolysis of terminal, non-reducing 2-acetamido-2-deoxy-beta-glucose residues in chitobiose and higher analogs as well as in glycoproteins. Has been used widely in structural studies on bacterial cell walls and in the study of diseases such as MUCOLIPIDOSIS and various inflammatory disorders of muscle and connective tissue.
MeSH Number(s)
D08.811.277.450.483.180.500
Concept/Terms
Acetylglucosaminidase- Acetylglucosaminidase
- beta-D-N-acetylglucosaminidase
- beta D N acetylglucosaminidase
- beta-N-Acetylglucosaminidase
- beta N Acetylglucosaminidase
- NAGase
- N,N-Diacetylchitobiase
- N,N Diacetylchitobiase
- N-Ac-beta-Glucosaminidase
- N Ac beta Glucosaminidase
- N-Acetyl-beta-D-glucosaminidase
- N Acetyl beta D glucosaminidase
- beta-D-Acetamido-2-Deoxyglucosidase
- beta D Acetamido 2 Deoxyglucosidase
- Chitobiase
Below are MeSH descriptors whose meaning is more general than "Acetylglucosaminidase".
Below are MeSH descriptors whose meaning is more specific than "Acetylglucosaminidase".
This graph shows the total number of publications written about "Acetylglucosaminidase" by people in Harvard Catalyst Profiles by year, and whether "Acetylglucosaminidase" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 2 | 0 | 2 |
| 1996 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 2000 | 1 | 1 | 2 |
| 2001 | 1 | 0 | 1 |
| 2002 | 0 | 2 | 2 |
| 2003 | 1 | 0 | 1 |
| 2004 | 0 | 2 | 2 |
| 2007 | 2 | 1 | 3 |
| 2008 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 1 | 2 |
| 2012 | 1 | 1 | 2 |
| 2014 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 1 | 1 | 2 |
| 2018 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
Below are the most recent publications written about "Acetylglucosaminidase" by people in Profiles.
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Biochemical evaluation of intracerebroventricular rhNAGLU-IGF2 enzyme replacement therapy in neonatal mice with Sanfilippo B syndrome. Mol Genet Metab. 2021 06; 133(2):185-192.
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Proteomic Analysis of Mucopolysaccharidosis IIIB Mouse Brain. Biomolecules. 2020 02 26; 10(3).
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Structural characterization of the a-N-acetylglucosaminidase, a key enzyme in the pathogenesis of Sanfilippo syndrome B. J Struct Biol. 2019 03 01; 205(3):65-71.
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Trehalose reduces retinal degeneration, neuroinflammation and storage burden caused by a lysosomal hydrolase deficiency. Autophagy. 2018; 14(8):1419-1434.
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Worsening Renal Function in Patients With Acute Heart Failure Undergoing Aggressive Diuresis Is Not Associated With Tubular Injury. Circulation. 2018 05 08; 137(19):2016-2028.
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Bisphenol A Exposure Impairs Epididymal Development during the Peripubertal Period of Rats: Inflammatory Profile and Tissue Changes. Basic Clin Pharmacol Toxicol. 2018 Feb; 122(2):262-270.
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Urine Kidney Injury Biomarkers and Risks of Cardiovascular Disease Events and All-Cause Death: The CRIC Study. Clin J Am Soc Nephrol. 2017 May 08; 12(5):761-771.
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Urine biomarkers of tubular injury do not improve on the clinical model predicting chronic kidney disease progression. Kidney Int. 2017 01; 91(1):196-203.
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Plasma kidney injury molecule-1 in heart failure: renal mechanisms and clinical outcome. Eur J Heart Fail. 2016 06; 18(6):641-9.
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Evidence of uncoupling between renal dysfunction and injury in cardiorenal syndrome: insights from the BIONICS study. PLoS One. 2014; 9(11):e112313.